LOCUS CCP46134.1 427 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Probable thymidine phosphorylase
DeoA (tdrpase) (pyrimidine phosphorylase) protein.
ACCESSION AL123456-3412
PROTEIN_ID CCP46134.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene="deoA"
/locus_tag="Rv3314c"
/note="Rv3314c, (MTV016.14), len: 427 aa. Probable
deoA,thymidine phosporylase, highly similar to many e.g.
Q9AK36|DEOA from Streptomyces coelicolor (427 aa), FASTA
scores: opt: 1668, E(): 3.2e-90, (62.35% identity in 425
aa overlap); Q9CFM5|PDP from Lactococcus lactis (subsp.
lactis) (Streptococcus lactis) (430 aa), FASTA scores:
opt: 1031, E(): 5.5e-53, (46.45% identity in 392 aa
overlap); P19971|TYPH_HUMAN|ECGF1 from Homo sapiens
(Human) (482 aa),FASTA scores: opt: 957, E(): 1.3e-48,
(44.45% identity in 441 aa overlap);
P07650|TYPH_ECOLI|DEOA|TPP|TTG|B4382 from Escherichia coli
strain K12 (440 aa), FASTA scores: opt: 847, E(): 3.2e-42,
(41.55% identity in 438 aa overlap); etc. Contains PS00647
Thymidine and pyrimidine-nucleoside phosphorylases
signature. Belongs to the thymidine/pyrimidine-nucleoside
phosphorylases family."
/db_xref="EnsemblGenomes-Gn:Rv3314c"
/db_xref="EnsemblGenomes-Tr:CCP46134"
/db_xref="GOA:P9WFS1"
/db_xref="InterPro:IPR000053"
/db_xref="InterPro:IPR000312"
/db_xref="InterPro:IPR013102"
/db_xref="InterPro:IPR017459"
/db_xref="InterPro:IPR017872"
/db_xref="InterPro:IPR018090"
/db_xref="InterPro:IPR035902"
/db_xref="InterPro:IPR036320"
/db_xref="InterPro:IPR036566"
/db_xref="UniProtKB/Swiss-Prot:P9WFS1"
/inference="protein motif:PROSITE:PS00647"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MTDFAFDAPT VIRTKRDGGR LSDAAIDWVV KAYTDGRVAD EQMSALLMAI VWRGMDRGEI
61 ARWTAAMLAS GARLDFTDLP LATVDKHSTG GVGDKITLPL VPVVAACGGA VPQASGRGLG
121 HTGGTLDKLE SITGFTANLS NQRVREQLCD VGAAIFAAGQ LAPADAKLYA LRDITGTVES
181 LPLIASSIMS KKLAEGAGAL VLDVKVGSGA FMRSPVQARE LAHTMVELGA AHGVPTRALL
241 TEMNCPLGRT VGNALEVAEA LEVLAGGGPP DVVELTLRLA GEMLELAGIH GRDPAQTLRD
301 GTAMDRFRRL VAAQGGDLSK PLPIGSHSET VTAGASGTMG DIDAMAVGLA AWRLGAGRSR
361 PGARVQHGAG VRIHRRPGEP VVVGEPLFTL YTNAPERFGA ARAELAGGWS IRDSPPQVRP
421 LIVDRIV
//