LOCUS       CCP46126.1               268 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Probable purine nucleoside
            phosphorylase DeoD (inosine phosphorylase) (PNP) protein.
ACCESSION   AL123456-3404
PROTEIN_ID  CCP46126.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="deoD"
                     /gene_synonym="punA"
                     /locus_tag="Rv3307"
                     /note="Rv3307, (MTV016.06), len: 268 aa. Probable deoD
                     (alternate gene name: punA), purine nucleoside
                     phosphorylase, similar to others especially
                     P46862|PUNA_MYCLE|DEOD_MYCLE|ML0707|L308_F2_56 from M.
                     leprae (268 aa), FASTA scores: opt: 1373, E():
                     1.5e-74,(82.05% identity in 262 aa overlap);
                     Q9EWV2|2SCK31.24 from Streptomyces coelicolor (274 aa),
                     FASTA scores: opt: 1026,E(): 6.4e-54, (60.5% identity in
                     266 aa overlap); P81989|PUNA_CELSP from Cellulomonas sp
                     (282 aa), FASTA scores: opt: 963, E(): 3.6e-50, (58.9%
                     identity in 270 aa overlap); Q9X1T2|TM1596 from Thermotoga
                     maritima (265 aa),FASTA scores: opt: 584, E(): 1.1e-27,
                     (39.55% identity in 263 aa overlap); etc. Belongs to the
                     PNP/MTAP family 2 of phosphorylases."
                     /db_xref="EnsemblGenomes-Gn:Rv3307"
                     /db_xref="EnsemblGenomes-Tr:CCP46126"
                     /db_xref="GOA:P9WP01"
                     /db_xref="InterPro:IPR000845"
                     /db_xref="InterPro:IPR011268"
                     /db_xref="InterPro:IPR011269"
                     /db_xref="InterPro:IPR018099"
                     /db_xref="InterPro:IPR035994"
                     /db_xref="PDB:1G2O"
                     /db_xref="PDB:1I80"
                     /db_xref="PDB:1N3I"
                     /db_xref="PDB:3IOM"
                     /db_xref="PDB:3SCZ"
                     /db_xref="UniProtKB/Swiss-Prot:P9WP01"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MADPRPDPDE LARRAAQVIA DRTGIGEHDV AVVLGSGWLP AVAALGSPTT VLPQAELPGF
       61 VPPTAAGHAG ELLSVPIGAH RVLVLAGRIH AYEGHDLRYV VHPVRAARAA GAQIMVLTNA
      121 AGGLRADLQV GQPVLISDHL NLTARSPLVG GEFVDLTDAY SPRLRELARQ SDPQLAEGVY
      181 AGLPGPHYET PAEIRMLQTL GADLVGMSTV HETIAARAAG AEVLGVSLVT NLAAGITGEP
      241 LSHAEVLAAG AASATRMGAL LADVIARF
//