LOCUS CCP46100.1 177 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Probable bifunctional
protein acetyl-/propionyl-coenzyme A carboxylase (epsilon
chain) AccE5 protein.
ACCESSION AL123456-3378
PROTEIN_ID CCP46100.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene="accE5"
/locus_tag="Rv3281"
/note="Rv3281, (MTCY71.21), len: 177 aa. Probable
accE5,bifunctional acetyl-/propionyl-coenzyme A
carboxylase,epsilon chain, equivalent (but longer 14 aa
and with a gap between aa 82-102) to AAK47723|MT3380 from
Mycobacterium tuberculosis strain CDC1551 (142 aa), FASTA
scores: opt: 830, E(): 3.1e-40, (86.5% identity in 163 aa
overlap). C-terminus highly similar to
Q49671|B1308_C3_211|ML0730 from Mycobacterium leprae (84
aa), FASTA scores: opt: 393,E(): 7.6e-16, (68.95% identity
in 87 aa overlap). A core mycobacterial gene; conserved in
mycobacterial strains (See Marmiesse et al., 2004). AccA3
(Rv3285), AccD5 (Rv3280),AccD4 (Rv3799), and AccE5
(Rv3281) form a biotin-dependent acyl-CoA carboxylase in
M. tuberculosis H37Rv (See Oh et al., 2006)."
/db_xref="EnsemblGenomes-Gn:Rv3281"
/db_xref="EnsemblGenomes-Tr:CCP46100"
/db_xref="GOA:P96886"
/db_xref="InterPro:IPR032716"
/db_xref="UniProtKB/TrEMBL:P96886"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MGTCPCESSE RNEPVSRVSG TNEVSDGNET NNPAEVSDGN ETNNPAEVSD GNETNNPAPV
61 SRVSGTNEVS DGNETNNPAP VSRVSGTNEV SDGNETNNPA PVTEKPLHPH EPHIEILRGQ
121 PTDQELAALI AVLGSISGST PPAQPEPTRW GLPVDQLRYP VFSWQRITLQ EMTHMRR
//