LOCUS CCP46072.1 495 aa PRT BCT 27-FEB-2015 DEFINITION Mycobacterium tuberculosis H37Rv Possible cationic amino acid transport integral membrane protein protein. ACCESSION AL123456-3350 PROTEIN_ID CCP46072.1 SOURCE Mycobacterium tuberculosis H37Rv ORGANISM Mycobacterium tuberculosis H37Rv Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III., Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R., Devlin K., Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L., Oliver K., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J., Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. TITLE Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence JOURNAL Nature 393(6685), 537-544(1998). PUBMED 9634230 REMARK Erratum:[Nature 1998 Nov 12;396(6707):190] REFERENCE 2 AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T. TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002). PUBMED 12368430 REFERENCE 3 AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T. TITLE TubercuList--10 years after JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011). PUBMED 20980199 REFERENCE 4 (bases 1 to 4411529) AUTHORS Parkhill J. JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the Mycobacterium tuberculosis sequencing and mapping teams, Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail: parkhill@sanger.ac.uk REFERENCE 5 (bases 1 to 4411532) AUTHORS Lew J.M. JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva 4, SWITZERLAND COMMENT On or before Feb 1, 2013 this sequence version replaced gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250, gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756, gi:38490319, gi:41352785, gi:38490370, gi:41353971. Note: This annotation is from the TubercuList website, Release 26, Dec 2012 (URL: http://tuberculist.epfl.ch) (email: tuberculist@epfl.ch). FEATURES Qualifiers source /organism="Mycobacterium tuberculosis H37Rv" /strain="H37Rv" /mol_type="genomic DNA" /db_xref="taxon:83332" protein /transl_table=11 /locus_tag="Rv3253c" /note="Rv3253c, (MTCY20B11.28c), len: 495 aa. Possible cationic amino acid transporter, integral membrane protein,similar to many e.g. O69844|SC1C3.02 putative cationic amino acid transporter from Streptomyces coelicolor (503 aa), FASTA scores: opt: 1649, E(): 5.8e-92, (52.6% identity in 485 aa overlap); Q9AE69 putative transporter (fragment) from Rhodococcus erythropolis (385 aa), FASTA scores: opt: 1594, E(): 9.7e-89, (62.0% identity in 387 aa overlap); Q9PBD7|XF2207 cationic amino acid transporter from Xylella fastidiosa (483 aa), FASTA scores: opt: 1079, E(): 1.2e-57,(40.55% identity in 493 aa overlap); Q9SRU9|F20H23.25 putative cationic amino acid transporter from Arabidopsis thaliana (Mouse-ear cress) (614 aa), FASTA scores: opt: 802, E(): 6.7e-41, (36.4% identity in 445 aa overlap); P30823|CTR1_RAT|SLC7A1|ATRC1 high-affinity cationic amino acid transporter-1 from Rattus norvegicus (Rat) (624 aa),FASTA scores: opt: 782, E(): 1.1e-39, (36.1% identity in 432 aa overlap); etc. Relatives in Mycobacterium tuberculosis include: MTCY3G12.14, E(): 5.6e-31; MTCY39.19,E(): 1.6e-14. Seems to belong to the APC family." /db_xref="EnsemblGenomes-Gn:Rv3253c" /db_xref="EnsemblGenomes-Tr:CCP46072" /db_xref="GOA:O05896" /db_xref="InterPro:IPR002293" /db_xref="UniProtKB/TrEMBL:O05896" /experiment="EXISTENCE: identified in proteomics study" BEGIN 1 MAGRRRMKSV EQSIADTDEP TTRLRKDLTW WDLVVFGVSV VIGAGIFTVT ASTAGDITGP 61 AIWISFLIAA ATCALAALCY AEFASTLPVA GSAYTFSYAT FGEFLAWVIG WNLVLELAMG 121 AAVVAKGWSS YLGTVFGFGN GTGHLGSLQL DWGALVIVTL VATLIALGTK LSSRFSAVVT 181 AIKVSVVVLV VVVGAFYIRA ANYSPFIPEP EVQHHGGGLD QSVFSLLTGA QGSHYGWYGV 241 LAGASIVFFA FIGFDIVATM AEETKRPQRD VPRGILASLG VVTLLYVAVS VVLSGMVPYT 301 QLRTVPGRGP ANLATAFQAN GVYWASGIIS VGALAGLTTV VMVLMLGQCR VLFAMARDGL 361 VPRQLAKTGS RGTPVRVTVL VAVLVATTAS VFPITKLEEM VNVGTLFAFI LVSAGVVVLR 421 RTRPDLQRGF TAPWVPLLPI AAVCACLWLM LNLTALTWIR FGIWLVAGTA IYVGYGRRHS 481 AQGLRQARES ATRRC //