LOCUS       CCP46064.1               567 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Two component sensory
            transduction histidine kinase MtrB protein.
ACCESSION   AL123456-3342
PROTEIN_ID  CCP46064.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="mtrB"
                     /locus_tag="Rv3245c"
                     /note="Rv3245c, (MTCY20B11.20c), len: 567 aa.
                     MtrB,sensor-like histidine kinase (see citations
                     below),equivalent to Q9CCJ1|MTRB or ML0774 putative
                     two-component system sensor kinase from Mycobacterium
                     leprae (562 aa),FASTA scores: opt: 3208, E(): 7.4e-173,
                     (88.7% identity in 566 aa overlap). Also similar to others
                     e.g. Q9KYW9|SCE33.14c putative two-component system
                     histidine kinase from Streptomyces coelicolor (688 aa),
                     FASTA scores: opt: 1355, E(): 1.1e-68, (48.95% identity in
                     515 aa overlap); etc. Relatives in Mycobacterium
                     tuberculosis are: MTCY369.03, E(): 1.5e-22; MTCY20G9.16,
                     E(): 1.9e-17. Similar to other prokaryotic sensory
                     transduction histidine kinases."
                     /db_xref="EnsemblGenomes-Gn:Rv3245c"
                     /db_xref="EnsemblGenomes-Tr:CCP46064"
                     /db_xref="GOA:P9WGK9"
                     /db_xref="InterPro:IPR003594"
                     /db_xref="InterPro:IPR003660"
                     /db_xref="InterPro:IPR003661"
                     /db_xref="InterPro:IPR004358"
                     /db_xref="InterPro:IPR005467"
                     /db_xref="InterPro:IPR036097"
                     /db_xref="InterPro:IPR036890"
                     /db_xref="UniProtKB/Swiss-Prot:P9WGK9"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MIFGSRRRIR GRRGRSGPMT RGLSALSRAV AVAWRRSLQL RVVALTLGLS LAVILALGFV
       61 LTSQVTNRVL DIKVRAAIDQ IERARTTVSG IVNGEETRSL DSSLQLARNT LTSKTDPASG
      121 AGLAGAFDAV LMVPGDGPRA ASTAGPVDQV PNALRGFVKA GQAAYQYATV QTEGFSGPAL
      181 IIGTPTLSRV ANLELYLIFP LASEQATITL VRGTMATGGL VLLVLLAGIA LLVSRQVVVP
      241 VRSASRIAER FAEGHLSERM PVRGEDDMAR LAVSFNDMAE SLSRQIAQLE EFGNLQRRFT
      301 SDVSHELRTP LTTVRMAADL IYDHSADLDP TLRRSTELMV SELDRFETLL NDLLEISRHD
      361 AGVAELSVEA VDLRTTVNNA LGNVGHLAEE AGIELLVDLP AEQVIAEVDA RRVERILRNL
      421 IANAIDHAEH KPVRIRMAAD EDTVAVTVRD YGVGLRPGEE KLVFSRFWRS DPSRVRRSGG
      481 TGLGLAISVE DARLHQGRLE AWGEPGEGAC FRLTLPMVRG HKVTTSPLPM KPIPQPVLQP
      541 VAQPNPQPMP PEYKERQRPR EHAEWSG
//