LOCUS       CCP46023.1               228 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Probable transcriptional
            regulatory protein (probably TetR-family) protein.
ACCESSION   AL123456-3301
PROTEIN_ID  CCP46023.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /locus_tag="Rv3208"
                     /note="Rv3208, (MTCY07D11.18c), len: 228 aa. Probable
                     transcriptional regulator, TetR family, equivalent to
                     Q9CCH0|ML0815 putative TetR-family transcriptional
                     regulator from Mycobacterium leprae (228 aa), FASTA
                     scores: opt: 1248, E(): 1.4e-74, (82.4% identity in 227 aa
                     overlap). Also highly similar to Q9FBI8|SCP8.33c putative
                     TetR-family transcriptional regulator from Streptomyces
                     coelicolor (213 aa), FASTA scores: opt: 629, E():
                     4e-34,(45.8% identity in 203 aa overlap); Q9KIL9|F58R F58R
                     (fragment) from Streptomyces coelicolor A3(2) (149
                     aa),FASTA scores: opt: 497, E(): 1.3e-25, (50.35% identity
                     in 147 aa overlap); Q9K3T5|SCE66.08 putative TetR-family
                     transcriptional regulator from Streptomyces coelicolor
                     (225 aa), FASTA scores: opt: 344, E(): 1.8e-15, (31.15%
                     identity in 212 aa overlap); Q9RYK4|DRA0308
                     transcriptional regulator, TetR family from Deinococcus
                     radiodurans (239 aa), FASTA scores: opt: 290, E():
                     6.5e-12, (30.5% identity in 223 aa overlap); etc. And also
                     similar to Mycobacterium tuberculosis proteins
                     P96381|Rv1019|MTCY10G2.30c hypothetical 21.7 KDA protein
                     (197 aa), FASTA scores: opt: 356, E(): 2.7e-16, (34.4%
                     identity in 189 aa overlap); MTV034_4; MTY07A7A_3;
                     MTV032_1; MTCY07A7_12; etc. Contains probable
                     helix-turn-helix motif at aa 60-81 (Score 1517,+4.35 SD).
                     Similar to the TetR/AcrR family of transcriptional
                     regulators."
                     /db_xref="EnsemblGenomes-Gn:Rv3208"
                     /db_xref="EnsemblGenomes-Tr:CCP46023"
                     /db_xref="GOA:O05858"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR036271"
                     /db_xref="UniProtKB/TrEMBL:O05858"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MSDLAKTAQR RALRSSGSAR PDEDVPAPNR RGNRLPRDER RGQLLVVASD VFVDRGYHAA
       61 GMDEIADRAG VSKPVLYQHF SSKLELYLAV LHRHVENLVS GVHQALSTTT DNRQRLHVAV
      121 QAFFDFIEHD SQGYRLIFEN DFVTEPEVAA QVRVATESCI DAVFALISAD SGLDPHRARM
      181 IAVGLVGMSV DCARYWLDAD KPISKSDAVE GTVQFAWGGL SHVPLTRS
//