LOCUS CCP45978.1 208 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Probable transcriptional
regulatory protein (probably TetR-family) protein.
ACCESSION AL123456-3256
PROTEIN_ID CCP45978.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/locus_tag="Rv3167c"
/note="Rv3167c, (MTV014.11c), len: 208 aa. Probable
transcriptional regulator, TetR family, similar to several
transcriptional regulators e.g. Q9L2A4|SC8F4.22c
(TetR/AcrR family) from Streptomyces coelicolor (234 aa),
FASTA scores: opt: 317, E(): 7.5e-13, (33.35% identity in
210 aa overlap); Q9RK47|SCF12.11 (TetR/AcrR family) from
Streptomyces coelicolor (206 aa), FASTA scores: opt:
293,E(): 2.1e-11, (32.65% identity in 199 aa overlap);
Q54288 regulator of antibiotic transport complexes
(TetR/AcrR family) (204 aa), FASTA scores: opt: 260, E():
2.4e-09,(30.75% identity in 205 aa overlap); etc.
Equivalent to AAK47595 from Mycobacterium tuberculosis
strain CDC1551 but shorter 21 aa. Contains probable
helix-turn-helix motif from aa 42 to 63 (Score 1727, +5.07
SD). May belong to the TetR/AcrR family of transcriptional
regulators."
/db_xref="EnsemblGenomes-Gn:Rv3167c"
/db_xref="EnsemblGenomes-Tr:CCP45978"
/db_xref="GOA:O53317"
/db_xref="InterPro:IPR001647"
/db_xref="InterPro:IPR009057"
/db_xref="InterPro:IPR011075"
/db_xref="InterPro:IPR036271"
/db_xref="UniProtKB/TrEMBL:O53317"
BEGIN
1 MKADLPSLDK APGAGRPRDP RIDSAILSAT AELLVQIGYS NLSLAAVAER AGTTKSALYR
61 RWSSKAELVH EAAFPAAPTA LQAAAGDIAA DIRMMIAATR DVFTTPVVRA ALPGLVADMT
121 ADAELNARVL ARFADLFAAV RMRLREAVDR GEAHPDVDPD RLIELIGGAT MLRMLLYPDD
181 MLDDAWVDQT TAIVVRGVHR AAPGGSVV
//