LOCUS CCP45962.1 806 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Probable NADH dehydrogenase
I (chain G) NuoG (NADH-ubiquinone oxidoreductase chain
G) protein.
ACCESSION AL123456-3240
PROTEIN_ID CCP45962.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene="nuoG"
/locus_tag="Rv3151"
/note="Rv3151, (MTCY03A2.07c), len: 806 aa. Probable
nuoG,NADH dehydrogenase I, chain G, similar to others e.g.
Q9XAR0|NUOG_STRCO from Streptomyces coelicolor (843
aa),FASTA scores: opt: 1968 ,E(): 5.2e-107, (62.45%
identity in 818 aa overlap); P56914|NUG2_RHIME from
Rhizobium meliloti (853 aa), FASTA scores: opt: 964, E():
1.6e-48, (30.6% identity in 840 aa overlap); etc. But also
similarity with other proteins e.g. P77908|FDHA formate
dehydrogenase,alpha subunit (formate dehydrogenase
[NADP+]) from Moorella thermoacetica (Clostridium
thermoaceticum) (893 aa), FASTA scores: opt: 928, E():
2e-46, (28.65% identity in 865 aa overlap); and
Q9UUU3|NUAM NUAM protein precursor from Yarrowia
lipolytica (Candida lipolytica) (728 aa), FASTA scores:
opt: 894, E(): 1.7e-44, (31.95% identity in 676 aa
overlap). Equivalent to AAK47578 from Mycobacterium
tuberculosis strain CDC1551 but longer 15 aa. Contains
respiratory-chain NADH dehydrogenase 75 kDa subunit
signature 2 (PS00642). Belongs to the complex I 75 KDA
subunit family. Cofactor: may bind two 4FE-4S cluster and
one 2FE-2S cluster."
/db_xref="EnsemblGenomes-Gn:Rv3151"
/db_xref="EnsemblGenomes-Tr:CCP45962"
/db_xref="GOA:P9WIV9"
/db_xref="InterPro:IPR000283"
/db_xref="InterPro:IPR001041"
/db_xref="InterPro:IPR006656"
/db_xref="InterPro:IPR006657"
/db_xref="InterPro:IPR006963"
/db_xref="InterPro:IPR009010"
/db_xref="InterPro:IPR010228"
/db_xref="InterPro:IPR019574"
/db_xref="InterPro:IPR036010"
/db_xref="UniProtKB/Swiss-Prot:P9WIV9"
/inference="protein motif:PROSITE:PS00642"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MTQAADTDIR VGQPEMVTLT IDGVEISVPK GTLVIRAAEL MGIQIPRFCD HPLLEPVGAC
61 RQCLVEVEGQ RKPLASCTTV ATDDMVVRTQ LTSEIADKAQ HGVMELLLIN HPLDCPMCDK
121 GGECPLQNQA MSNGRTDSRF TEAKRTFAKP INISAQVLLD RERCILCARC TRFSDQIAGD
181 PFIDMQERGA LQQVGIYADE PFESYFSGNT VQICPVGALT GTAYRFRARP FDLVSSPSVC
241 EHCASGCAQR TDHRRGKVLR RLAGDDPEVN EEWNCDKGRW AFTYATQPDV ITTPLIRDGG
301 DPKGALVPTS WSHAMAVAAQ GLAAARGRTG VLVGGRVTWE DAYAYAKFAR ITLGTNDIDF
361 RARPHSAEEA DFLAARIAGR HMAVSYADLE SAPVVLLVGF EPEDESPIVF LRLRKAARRH
421 RVPVYTIAPF ATGGLHKMSG RLIKTVPGGE PAALDDLATG AVGDLLATPG AVIIVGERLA
481 TVPGGLSAAA RLADTTGARL AWVPRRAGER GALEAGALPT LLPGGRPLAD EVARAQVCAA
541 WHIAELPAAA GRDADGILAA AADETLAALL VGGIEPADFA DPDAVLAALD ATGFVVSLEL
601 RHSTVTERAD VVFPVAPTTQ KAGAFVNWEG RYRTFEPALR GSTLQAGQSD HRVLDALADD
661 MGVHLGVPTV EAAREELAAL GIWDGKHAAG PHIAATGPTQ PEAGEAILTG WRMLLDEGRL
721 QDGEPYLAGT ARTPVVRLSP DTAAEIGAAD GEAVTVSTSR GSITLPCSVT DMPDRVVWLP
781 LNSAGSTVHR QLRVTIGSIV KIGAGS
//