LOCUS       CCP45915.1               378 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Probable peptide chain
            release factor 2 PrfB (RF-2) protein.
ACCESSION   AL123456-3193
PROTEIN_ID  CCP45915.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="prfB"
                     /locus_tag="Rv3105c"
                     /note="Rv3105c, (MTCY164.15c), len: 378 aa. Probable
                     prfB,peptide chain release factor 2, equivalent to
                     O32885|RF2_MYCLE|ML0667|MLCB1779.24c from Mycobacterium
                     leprae, FASTA scores: opt: 2197, E(): 1.8e-126, (90.05%
                     identity in 372 aa overlap); and also similar to other
                     peptide chain release factors e.g. Q9L1S3|PRFB from
                     Streptomyces coelicolor (368 aa), FASTA scores: opt:
                     1674,E(): 1.2e-94, (69.3% identity in 365 aa overlap);
                     O67695|RF2_AQUAE|PRFB|AQ_1840 from Aquifex aeolicus (373
                     aa), FASTA scores: opt: 1082, E(): 1.3e-58, (44.45%
                     identity in 369 aa overlap); P28367|RF2_BACSU from B.
                     subtilis (366 aa), FASTA scores: opt: 1030, E():
                     1.9e-55,(44.0% identity in 359 aa overlap); etc. Also
                     related to Q10605|MTCY373.19|RF1_MYCTU|Rv1299|MT1338
                     peptide chain release factor 1 (rf-1) (357 aa), FASTA
                     scores: opt: 646,E(): 1.1e-34, (38.6% identity in 350 aa
                     overlap). Contains prokaryotic-type class I peptide chain
                     release factors signature (PS00745). Belongs to the
                     prokaryotic and mitochondrial release factors family."
                     /db_xref="EnsemblGenomes-Gn:Rv3105c"
                     /db_xref="EnsemblGenomes-Tr:CCP45915"
                     /db_xref="GOA:P9WHG1"
                     /db_xref="InterPro:IPR000352"
                     /db_xref="InterPro:IPR004374"
                     /db_xref="InterPro:IPR005139"
                     /db_xref="UniProtKB/Swiss-Prot:P9WHG1"
                     /inference="protein motif:PROSITE:PS00745"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MPVTLAAVDP DRQADIAALD CTLTTVERVL DVEGLRSRIE KLEHEASDPH LWDDQTRAQR
       61 VTSELSHTQG ELRRVEELRR RLDDLPVLYE LAAEEAGAAA ADAVAEADAE LKSLRADIEA
      121 TEVRTLLSGE YDEREALVTI RSGAGGVDAA DWAEMLMRMY IRWAEQHKYP VEVFDTSYAE
      181 EAGIKSATFA VHAPFAYGTL SVEQGTHRLV RISPFDNQSR RQTSFAEVEV LPVVETTDHI
      241 DIPEGDVRVD VYRSSGPGGQ SVNTTDSAVR LTHIPSGIVV TCQNEKSQLQ NKIAAMRVLQ
      301 AKLLERKRLE ERAELDALKA DGGSSWGNQM RSYVLHPYQM VKDLRTEYEV GNPAAVLDGD
      361 LDGFLEAGIR WRNRRNDD
//