LOCUS CCP45815.1 509 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Probable glutamyl-tRNA(
GLN) amidotransferase (subunit B) GatB (Glu-ADT subunit
B) protein.
ACCESSION AL123456-3093
PROTEIN_ID CCP45815.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene="gatB"
/locus_tag="Rv3009c"
/note="Rv3009c, (MT3089, MTV012.23c), len: 509 aa.
Probable gatB, Glu- tRNA-Gln amidotransferase, subunit B
,equivalent to O33107|GATB_MYCLE|MLCB637_15
glutamyl-tRNA(GLN) amidotransferase from Mycobacterium
leprae (509 aa), FASTA scores: opt: 2973, E():
2.9e-173,(88.4% identity in 509 aa overlap). Also highly
similar to other Glu- tRNA-Gln amidotransferases e.g.
Q9Z578|GATB|SC8D9.13 from Streptomyces coelicolor (504
aa),FASTA scores: opt: 2264, E(): 3.6e-130, (66.0%
identity in 495 aa overlap); P74215|GATB_SYNY3|SLL1435
from Synechocystis sp. strain PCC 6803 (519 aa), FASTA
scores: opt: 1289, E(): 6.7e-71, (42.0% identity in 485 aa
overlap); Q9X100|GATB_THEMA|TM1273 glutamyl-tRNA(GLN)
amidotransferase from Thermotoga maritima (482 aa), FASTA
scores: opt: 1165, E(): 2.2e-63, (40.05% identity in 487
aa overlap); etc. For more information about function, see
citation below. Similar to many members of the pet112
family. Belongs to the GatB family."
/db_xref="EnsemblGenomes-Gn:Rv3009c"
/db_xref="EnsemblGenomes-Tr:CCP45815"
/db_xref="GOA:P9WN61"
/db_xref="InterPro:IPR003789"
/db_xref="InterPro:IPR004413"
/db_xref="InterPro:IPR006075"
/db_xref="InterPro:IPR014746"
/db_xref="InterPro:IPR017958"
/db_xref="InterPro:IPR017959"
/db_xref="InterPro:IPR018027"
/db_xref="InterPro:IPR023168"
/db_xref="InterPro:IPR042114"
/db_xref="UniProtKB/Swiss-Prot:P9WN61"
/inference="protein motif:PROSITE:PS00041"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MTVAAGAAKA AGAELLDYDE VVARFQPVLG LEVHVELSTA TKMFCGCTTT FGGEPNTQVC
61 PVCLGLPGSL PVLNRAAVES AIRIGLALNC EIVPWCRFAR KNYFYPDMPK NYQISQYDEP
121 IAINGYLDAP LEDGTTWRVE IERAHMEEDT GKLTHIGSET GRIHGATGSL IDYNRAGVPL
181 IEIVTKPIVG AGARAPQIAR SYVTALRDLL RALDVSDVRM DQGSMRCDAN VSLKPAGTTE
241 FGTRTETKNV NSLKSVEVAV RYEMQRQGAI LASGGRITQE TRHFHEAGYT SAGRTKETAE
301 DYRYFPEPDL EPVAPSRELV ERLRQTIPEL PWLSRRRIQQ EWGVSDEVMR DLVNAGAVEL
361 VAATVEHGAS SEAARAWWGN FLAQKANEAG IGLDELAITP AQVAAVVALV DEGKLSNSLA
421 RQVVEGVLAG EGEPEQVMTA RGLALVRDDS LTQAAVDEAL AANPDVADKI RGGKVAAAGA
481 IVGAVMKATR GQADAARVRE LVLEACGQG
//