LOCUS       CCP45782.1               333 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Probable thiamine-monophosphate
            kinase ThiL (thiamine-phosphate kinase) protein.
ACCESSION   AL123456-3060
PROTEIN_ID  CCP45782.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="thiL"
                     /locus_tag="Rv2977c"
                     /note="Rv2977c, (MTCY349.10), len: 333 aa. Possible
                     thiL,thiamin-monophosphate kinase, equivalent to Q9CBS2
                     probable thiamine-monophosphate kinase from Mycobacterium
                     leprae (325 aa), FASTA scores: opt: 1738, E(): 4.5e-98,
                     (80.9% identity in 314 aa overlap). Also highly similar to
                     others e.g. Q9ZBR7|SC7A1.06 putative thiamine monphosphate
                     kinase from Streptomyces coelicolor (322 aa), FASTA
                     scores: opt: 959, E(): 7.8e-51, (51.1% identity in 319 aa
                     overlap); O05514|THIL_BACSU thiamine-monophosphate kinase
                     from Bacillus subtilis (325 aa), FASTA scores: opt: 476,
                     E(): 1.5e-21, (35.15% identity in 273 aa overlap);
                     P77785|THIL_ECOLI|THIL|B0417 thiamine-monophosphate kinase
                     from Escherichia coli strain K12 (325 aa), FASTA scores:
                     opt: 418, E(): 5e-18, (36.9% identity in 282 aa overlap);
                     etc. Belongs to the thiamine-monophosphate kinase family.
                     Note that the start, as given, is in IS1538."
                     /db_xref="EnsemblGenomes-Gn:Rv2977c"
                     /db_xref="EnsemblGenomes-Tr:CCP45782"
                     /db_xref="GOA:P9WG71"
                     /db_xref="InterPro:IPR006283"
                     /db_xref="InterPro:IPR010918"
                     /db_xref="InterPro:IPR016188"
                     /db_xref="InterPro:IPR036676"
                     /db_xref="InterPro:IPR036921"
                     /db_xref="UniProtKB/Swiss-Prot:P9WG71"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MTTKDHSLAT ESPTLQQLGE FAVIDRLVRG RRQPATVLLG PGDDAALVSA GDGRTVVSTD
       61 MLVQDSHFRL DWSTPQDVGR KAIAQNAADI EAMGARATAF VVGFGAPAET PAAQASALVD
      121 GMWEEAGRIG AGIVGGDLVS CRQWVVSVTA IGDLDGRAPV LRSGAKAGSV LAVVGELGRS
      181 AAGYALWCNG IEDFAELRRR HLVPQPPYGH GAAAAAVGAQ AMIDVSDGLL ADLRHIAEAS
      241 GVRIDLSAAA LAADRDALTA AATALGTDPW PWVLSGGEDH ALVACFVGPV PAGWRTIGRV
      301 LDGPARVLVD GEEWTGYAGW QSFGEPDNQG SLG
//