LOCUS CCP45778.1 737 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Probable ATP-dependent
DNA helicase RecG protein.
ACCESSION AL123456-3056
PROTEIN_ID CCP45778.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene="recG"
/locus_tag="Rv2973c"
/note="Rv2973c, (MTCY349.14), len: 737 aa. Probable
recG,ATP-dependent DNA helicase (see citation below),
equivalent to O69460|RECG_MYCLE ATP-dependent DNA helicase
from Mycobacterium leprae (743 aa), FASTA scores: opt:
3846,E(): 0, (79.3% identity in 744 aa overlap). Also
highly similar to others e.g. Q9ZBR3|SC7A1.10 putative
ATP-dependent DNA helicase from Streptomyces coelicolor
(742 aa), FASTA scores: opt: 1249, E(): 1.1e-67, (46.2%
identity in 758 aa overlap); Q9PGE8 ATP-dependent DNA
helicase from Xylella fastidiosa (718 aa), FASTA scores:
opt: 1174, E(): 3.5e-63, (42.1% identity in 539 aa
overlap); P24230|RECG_ECOLI|RECG|B3652 from Escherichia
coli strain K12 (693 aa), FASTA scores: opt: 457, E():
7.3e-22, (35.2% identity in 733 aa overlap); etc. Contains
PS00017 ATP/GTP-binding site motif A (P-loop). Belongs to
the helicase family, RECG subfamily."
/db_xref="EnsemblGenomes-Gn:Rv2973c"
/db_xref="EnsemblGenomes-Tr:CCP45778"
/db_xref="GOA:P9WMQ7"
/db_xref="InterPro:IPR001650"
/db_xref="InterPro:IPR004609"
/db_xref="InterPro:IPR011545"
/db_xref="InterPro:IPR012340"
/db_xref="InterPro:IPR014001"
/db_xref="InterPro:IPR027417"
/db_xref="InterPro:IPR033454"
/db_xref="UniProtKB/Swiss-Prot:P9WMQ7"
/inference="protein motif:PROSITE:PS00017"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MASLSDRLDR VLGATAADAL DEQFGMRTVD DLLRHYPRSY VEGAARVGIG DARPEAGEHI
61 TIVDVITDTY SFPMKKKPNR KCLRITVGGG RNKVTATFFN ADYIMRDLTK HTKVMLSGEV
121 GYYKGAMQLT HPAFLILDSP DGKNHGTRSL KSIADASKAI SGELVVEEFE RRFFPIYPAS
181 TKVQSWDIFK CVRQVLDVLD RVDDPLPAEL RAKHGLIPED EALRAIHLAE SQSLRERARE
241 RLTFDEAVGL QWALVARRHG ELSESGPSAA WKSNGLAAEL LRRLPFELTA GQREVLDVLS
301 DGLAANRPLN RLLQGEVGSG KTIVAVLAML QMVDAGYQCA LLAPTEVLAA QHLRSIRDVL
361 GPLAMGGQLG GAENATRVAL LTGSMTAGQK KQVRAEIASG QVGIVIGTHA LLQEAVDFHN
421 LGMVVVDEQH RFGVEQRDQL RAKAPAGITP HLLVMTATPI PRTVALTVYG DLETSTLREL
481 PLGRQPIATN VIFVKDKPAW LDRAWRRIIE EAAAGRQAYV VAPRIDESDD TDVQGGVRPS
541 ATAEGLFSRL RSAELAELRL ALMHGRLSAD DKDAAMAAFR AGEVDVLVCT TVIEVGVDVP
601 NATVMLVMDA DRFGISQLHQ LRGRIGRGEH PSVCLLASWV PPDTPAGQRL RAVAGTMDGF
661 ALADLDLKER KEGDVLGRNQ SGKAITLRLL SLAEHEEYIV AARDFCIEAY KNPTDPALAL
721 MAARFTSTDR IEYLDKS
//