LOCUS       CCP45776.1               282 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Probable oxidoreductase protein.
ACCESSION   AL123456-3054
PROTEIN_ID  CCP45776.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /locus_tag="Rv2971"
                     /note="Rv2971, (MTCY349.16c), len: 282 aa. Probable
                     oxidoreductase, possibly aldo/keto reductase, equivalent
                     to O69462 putative oxidoreductase from Mycobacterium
                     leprae (282 aa), FASTA scores: opt: 1495, E(): 4.9e-93,
                     (82.35% identity in 272 aa overlap). Also similar to
                     others e.g. Q9KYM9|SC9H11.10C oxidoreductase from
                     Streptomyces coelicolor (276 aa), FASTA scores: opt: 849,
                     E(): 1.2e-49,(51.7% identity in 267 aa overlap);
                     Q9ZBW7|SC4B5.01C putative oxidoreductase from Streptomyces
                     coelicolor (277 aa), FASTA scores: opt: 847, E(): 1.7e-49,
                     (49.1% identity in 271 aa overlap);
                     Q46857|YQHE_ECOLI|YQHE|B3012 hypothetical oxidoreductase
                     from Escherichia coli strain K12 (275 aa), FASTA scores:
                     opt: 827, E(): 3.7e-48, (47.45% identity in 276 aa
                     overlap); etc. Contains PS00063 Aldo/keto reductase family
                     putative active site signature; and PS00062 Aldo/keto
                     reductase family signature 2."
                     /db_xref="EnsemblGenomes-Gn:Rv2971"
                     /db_xref="EnsemblGenomes-Tr:CCP45776"
                     /db_xref="GOA:P9WQA5"
                     /db_xref="InterPro:IPR018170"
                     /db_xref="InterPro:IPR020471"
                     /db_xref="InterPro:IPR023210"
                     /db_xref="InterPro:IPR036812"
                     /db_xref="PDB:4OTK"
                     /db_xref="UniProtKB/Swiss-Prot:P9WQA5"
                     /inference="protein motif:PROSITE:PS00062"
                     /inference="protein motif:PROSITE:PS00063"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MTGESGAAAA PSITLNDEHT MPVLGLGVAE LSDDETERAV SAALEIGCRL IDTAYAYGNE
       61 AAVGRAIAAS GVAREELFVT TKLATPDQGF TRSQEACRAS LDRLGLDYVD LYLIHWPAPP
      121 VGKYVDAWGG MIQSRGEGHA RSIGVSNFTA ENIENLIDLT FVTPAVNQIE LHPLLNQDEL
      181 RKANAQHTVV TQSYCPLALG RLLDNPTVTS IASEYVKTPA QVLLRWNLQL GNAVVVRSAR
      241 PERIASNFDV FDFELAAEHM DALGGLNDGT RVREDPLTYA GT
//