LOCUS       CCP45704.1               264 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Probable ribonuclease
            HII protein RnhB (RNase HII) protein.
ACCESSION   AL123456-2982
PROTEIN_ID  CCP45704.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="rnhB"
                     /locus_tag="Rv2902c"
                     /note="Rv2902c, (MT2970, MTCY274.33c), len: 264 aa.
                     Probable rnhB, ribonuclease HII, equivalent to
                     O33022|RNH2_MYCLE|RNHB|ML1611|MLCB250.40 ribonuclease HII
                     from Mycobacterium leprae (240 aa), FASTA scores: opt:
                     1242, E(): 6.9e-72, (76.75% identity in 245 aa overlap).
                     Also similar (but longer ~20 aa) to others e.g.
                     Q9HXY9|RNHB|PA3642 ribonuclease HII from Pseudomonas
                     aeruginosa (201 aa), FASTA scores: opt: 572, E():
                     3.1e-29,(52.7% identity in 184 aa overlap);
                     Q9PEI7|RNH2_XYLFA|RNHB|XF1041 ribonuclease HII from
                     Xylella fastidiosa (234 aa), FASTA scores: opt: 556, E():
                     3.6e-28,(50.25% identity in 185 aa overlap);
                     P10442|RNH2_ECOLI|RNHB|B0183 ribonuclease HII from
                     Escherichia coli strain K-12 (213 aa), FASTA scores: opt:
                     519, E(): 7.4e-26, (48.65% identity in 183 aa overlap);
                     etc. Belongs to the RNASE HII family. Cofactor: manganese
                     (by similarity)."
                     /db_xref="EnsemblGenomes-Gn:Rv2902c"
                     /db_xref="EnsemblGenomes-Tr:CCP45704"
                     /db_xref="GOA:P9WH01"
                     /db_xref="InterPro:IPR001352"
                     /db_xref="InterPro:IPR012337"
                     /db_xref="InterPro:IPR022898"
                     /db_xref="InterPro:IPR024567"
                     /db_xref="InterPro:IPR036397"
                     /db_xref="UniProtKB/Swiss-Prot:P9WH01"
BEGIN
        1 MTKTWPPRTV IRKSGGLRGM RTLESALHRG GLGPVAGVDE VGRGACAGPL VVAACVLGPG
       61 RIASLAALDD SKKLSEQARE KLFPLICRYA VAYHVVFIPS AEVDRRGVHV ANIEGMRRAV
      121 AGLAVRPGYV LSDGFRVPGL PMPSLPVIGG DAAAACIAAA SVLAKVSRDR VMVALDADHP
      181 GYGFAEHKGY STPAHSRALA RLGPCPQHRY SFINVRRVAS GSNTAEVADG QPDPRDGTAQ
      241 TGEGRWSKSS HPATMRATGR AQGT
//