LOCUS CCP45565.1 260 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Probable short-chain
type dehydrogenase/reductase protein.
ACCESSION AL123456-2843
PROTEIN_ID CCP45565.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene_synonym="fabG5"
/locus_tag="Rv2766c"
/note="Rv2766c, (MTV002.31c), len: 260 aa. Probable
short-chain dehydrogenase/reductase , similar to others
(from bacteria and eukaryota) e.g. Q9K3Y8|2SCG61.27c
putative short chain oxidoreductase from Streptomyces
coelicolor (253 aa), FASTA scores: opt: 722, E():
7.4e-39,(44.75% identity in 248 aa overlap);
Q93790|F54F3.4 hypothetical SDR protein from
Caenorhabditis elegans (260 aa), FASTA scores: opt: 613,
E(): 6.9e-32, (41.7% identity in 247 aa overlap);
O95162|O95162|scad-SRL peroxisomal short-chain alcohol
dehydrogenase from Homo sapiens (Human) (260 aa), FASTA
scores: opt: 594, E(): 1.1e-30, (39.6% identity in 250 aa
overlap); P51831|FABG_BACSU 3-oxoacyl-[acyl-carrier
protein] from Bacillus subtilis (246 aa), FASTA scores:
opt: 504, E(): 4e-28, (37.2% identity in 247 aa overlap);
etc. Also similar to many other Mycobacterium tuberculosis
acyl-carrier proteins e.g. MTCY03C7.07 (38.5% identity in
244 aa overlap). Contains PS00061 Short-chain alcohol
dehydrogenase family signature. Belongs to the short-chain
dehydrogenases/reductases (SDR) family. Note that
previously known as fabG5, a
3-oxoacyl-[acyl-carrier-protein]."
/db_xref="EnsemblGenomes-Gn:Rv2766c"
/db_xref="EnsemblGenomes-Tr:CCP45565"
/db_xref="GOA:I6YEB6"
/db_xref="InterPro:IPR002347"
/db_xref="InterPro:IPR020904"
/db_xref="InterPro:IPR036291"
/db_xref="UniProtKB/TrEMBL:I6YEB6"
/inference="protein motif:PROSITE:PS00061"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MTSLDLTGRT AIITGASRGI GLAIAQQLAA AGAHVVLTAR RQEAADEAAA QVGDRALGVG
61 AHAVDEDAAR RCVDLTLERF GSVDILINNA GTNPAYGPLL EQDHARFAKI FDVNLWAPLM
121 WTSLVVTAWM GEHGGAVVNT ASIGGMHQSP AMGMYNATKA ALIHVTKQLA LELSPRIRVN
181 AICPGVVRTR LAEALWKDHE DPLAATIALG RIGEPADIAS AVAFLVSDAA SWITGETMII
241 DGGLLLGNAL GFRAAPSTEH
//