LOCUS CCP45539.1 149 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Epoxide hydrolase protein.
ACCESSION AL123456-2817
PROTEIN_ID CCP45539.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene="ephG"
/locus_tag="Rv2740"
/note="Rv2740, (MTV002.05), len: 149 aa. EphG, Epoxide
hydrolase, proven biochemically (see Unge et al.
2005),similar to limonene-1,2-epoxide hydrolase capable of
hydrolyzing long or bulky lipophilic epoxides.
Equivalent,but shorter 17 aa, to Q9CCC2|ML0984 (alias
Q49850 but longer) hypothetical protein from Mycobacterium
leprae (164 aa), FASTA scores: opt: 481, E(): 9.7e-26,
(52.0% identity in 150 aa overlap). A core mycobacterial
gene; conserved in mycobacterial strains (See Marmiesse et
al., 2004)."
/db_xref="EnsemblGenomes-Gn:Rv2740"
/db_xref="EnsemblGenomes-Tr:CCP45539"
/db_xref="GOA:O33283"
/db_xref="InterPro:IPR013100"
/db_xref="InterPro:IPR032710"
/db_xref="PDB:2BNG"
/db_xref="UniProtKB/Swiss-Prot:O33283"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MAELTETSPE TPETTEAIRA VEAFLNALQN EDFDTVDAAL GDDLVYENVG FSRIRGGRRT
61 ATLLRRMQGR VGFEVKIHRI GADGAAVLTE RTDALIIGPL RVQFWVCGVF EVDDGRITLW
121 RDYFDVYDMF KGLLRGLVAL VVPSLKATL
//