LOCUS       CCP45483.1               428 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Probable arsenic-transport
            integral membrane protein ArsB1 protein.
ACCESSION   AL123456-2761
PROTEIN_ID  CCP45483.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="arsB1"
                     /gene_synonym="arsB"
                     /locus_tag="Rv2685"
                     /note="Rv2685, (MTCY05A6.06), len: 428 aa. Probable
                     arsB1,arsenic-transport integral membrane protein,
                     equivalent to P46838|AG45_MYCLE|ML1036 46 KDA probable
                     integral membrane protein (antigen 45, a transmembrane
                     protein related to arsenical pumps) from Mycobacterium
                     leprae (429 aa), FASTA scores: opt: 2048, E(): 7.3e-120,
                     (74.25% identity in 427 aa overlap); and downstream ORF
                     O07186|YQ84_MYCTU|ARSA|Rv2684|MT2758|MTCY05A6.05 probable
                     integral membrane protein ARSA from Mycobacterium
                     tuberculosis (429 aa), FASTA scores: opt: 2154, E():
                     1.9e-126, (76.8% identity in 427 aa overlap). Also highly
                     similar to other proteins e.g. O59575|PH1912 hypothetical
                     46.0 KDA protein from Pyrococcus horikoshii (424 aa),
                     FASTA scores: opt: 1075, E(): 1.9e-59, (43.55% identity in
                     427 aa overlap); Q9UY19|PAB1107 transport protein from
                     Pyrococcus abyssi (425 aa), FASTA scores: opt: 1062, E():
                     1.3e-58,(41.8% identity in 428 aa overlap); Q9KDI2|BH1231
                     hypothetical 46.0 KDA protein from Bacillus halodurans
                     (428 aa), FASTA scores: opt: 993, E(): 2.4e-54, (39.55%
                     identity in 430 aa overlap); etc. Belongs to the
                     NADC/P/PHO87 family of transporters, P subfamily. Note
                     that previously known as arsB."
                     /db_xref="EnsemblGenomes-Gn:Rv2685"
                     /db_xref="EnsemblGenomes-Tr:CCP45483"
                     /db_xref="GOA:P9WPD7"
                     /db_xref="InterPro:IPR000802"
                     /db_xref="InterPro:IPR004680"
                     /db_xref="UniProtKB/Swiss-Prot:P9WPD7"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MSIIAITVFV AGYALIASDR VSKTRVALTC AAIMVGAGIV GSDDVFYSHE AGIDWDVIFL
       61 LLGMMIIVSV LRHTGVFEYV AIWAVKRANA APLRIMILLV LVTALGSALL DNVTTVLLIA
      121 PVTLLVCDRL GVNSTPFLVA EVFASNVGGA ATLVGDPPNI IIASRAGLTF NDFLIHMAPA
      181 VLVVMIALIG LLPWLLGSVT AEPDRVADVL SLNEREAIHD RGLLIKCGVV LVLVFAAFIA
      241 HPVLHIQPSL VALLGAGVLV RFSGLERSDY LSSVEWDTLL FFAGLFVMVG ALVKTGVVEQ
      301 LARAATELTG GNELLTVGLI LGISAPVSGI IDNIPYVATM TPIVTELVAA MPGHVHPDTF
      361 WWALALSADF GGNLTAVAAS ANVVMLGIAR RSGTPISFWK FTRKGAVVTA VSLVLSAVYL
      421 WLRYFVFG
//