LOCUS CCP45471.1 433 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Possible arabinofuranosyltransferas
e AftC protein.
ACCESSION AL123456-2749
PROTEIN_ID CCP45471.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene="aftC"
/locus_tag="Rv2673"
/note="Rv2673, (MTCY441.42), len: 433 aa. Possible
aftC,arabinofuranosyltransferase (See Birch et al., 2008).
Predicted to be in the GT-C superfamily of
glycosyltransferases (See Liu and Mushegian, 2003).
Possible conserved integral membrane protein, equivalent
to MLC1351.25|ML1338 possible conserved integral membrane
protein from Mycobacterium leprae (440 aa), FASTA scores:
opt: 2410, E(): 5.3e-143, (82.05% identity in 434 aa
overlap); and showing some similarity with Q9CBX0|ML1504
probable conserved membrane protein from Mycobacterium
leprae (430 aa), FASTA scores: opt: 159, E(): 0.014,
(24.4% identity in 340 aa overlap). Also similar to
Q53873|SC6G4.11 putative integral membrane protein from
Streptomyces coelicolor (411 aa), FASTA scores: opt:
383,E(): 1.4e-16, (29.6% identity in 422 aa overlap); and
with weak similarity with P71061|YVFB hypothetical protein
from Bacillus subtilis (396 aa), FASTA scores: opt: 136,
E(): 0.36, (24.35% identity in 279 aa overlap); and
BAB60134|TVG1014811 hypothetical protein from Thermoplasma
volcanium (695 aa), FASTA scores: opt: 133, E():
0.85,(26.45% identity in 280 aa overlap). Shows also some
similarity with O06557|Rv1159|MTCI65.26 hypothetical 47.1
KDA protein from Mycobacterium tuberculosis (431 aa),
FASTA scores: opt: 149, E(): 0.059, (22.45% identity in
410 aa overlap); and O53515|Rv2181|MTV021.14 putative
membrane protein from Mycobacterium tuberculosis (427 aa),
FASTA scores: opt: 129, E(): 1, (24.8% identity in 367 aa
overlap)."
/db_xref="EnsemblGenomes-Gn:Rv2673"
/db_xref="EnsemblGenomes-Tr:CCP45471"
/db_xref="GOA:P9WMZ7"
/db_xref="InterPro:IPR018584"
/db_xref="UniProtKB/Swiss-Prot:P9WMZ7"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MYGALVTAAD SIRTGLGASL LAGFRPRTGA PSTATILRSA LWPAAVLSVL HRSIVLTTNG
61 NITDDFKPVY RAVLNFRRGW DIYNEHFDYV DPHYLYPPGG TLLMAPFGYL PFAPSRYLFI
121 SINTAAILVA AYLLLRMFNF TLTSVAAPAL ILAMFATETV TNTLVFTNIN GCILLLEVLF
181 LRWLLDGRAS RQWCGGLAIG LTLVLKPLLG PLLLLPLLNR QWRALVAAVV VPVVVNVAAL
241 PLVSDPMSFF TRTLPYILGT RDYFNSSILG NGVYFGLPTW LILFLRILFT AITFGALWLL
301 YRYYRTGDPL FWFTTSSGVL LLWSWLVMSL AQGYYSMMLF PFLMTVVLPN SVIRNWPAWL
361 GVYGFMTLDR WLLFNWMRWG RALEYLKITY GWSLLLIVTF TVLYFRYLDA KADNRLDGGI
421 DPAWLTPERE GQR
//