LOCUS CCP45265.1 546 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Probable alpha-glucosidase
AglA (maltase) (glucoinvertase) (glucosidosucrase) (maltase-
glucoamylase) (lysosomal alpha-glucosidase) (acid maltase)
protein.
ACCESSION AL123456-2543
PROTEIN_ID CCP45265.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene="aglA"
/locus_tag="Rv2471"
/note="Rv2471, (MTV008.27), len: 546 aa. Probable
aglA,maltase (alpha-glucosidase), highly similar or
similar to several e.g. Q60027|AGLA from Thermomonospora
curvata (544 aa), FASTA scores: opt: 2071, E(): 4e-116,
(57.7% identity in 525 aa overlap); Q9KZE3|AGLAE from
Streptomyces coelicolor (534 aa), FASTA scores: opt: 1475,
E(): 1.5e-80,(50.1% identity in 537 aa overlap);
O86874|AGLA from Streptomyces lividans (534 aa), FASTA
scores: opt: 1473,E(): 2e-80, (50.1% identity in 537 aa
overlap); etc. Seems to belong to family 13 of glycosyl
hydrolases, also known as the alpha-amylase family."
/db_xref="EnsemblGenomes-Gn:Rv2471"
/db_xref="EnsemblGenomes-Tr:CCP45265"
/db_xref="GOA:O53198"
/db_xref="InterPro:IPR006047"
/db_xref="InterPro:IPR017853"
/db_xref="UniProtKB/TrEMBL:O53198"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MDQHQRPDPM GPGSPRASAR RPEPDPMGEP WWSRAVFYQV YPRSFADSNG DGVGDLDGLA
61 SRLDHLQQLG VDAIWINPVT VSPMADHGYD VADPRDIDPL FGGMPAFERL VAAAHRQGIK
121 VTMDVVPNHT SSAHPWFQAA LADLPGSPAR DRYFFRDGRG PDGSLPPNNW ESVFGGPAWT
181 RVREPDGNPG QWYLHLFDTE QPDLNWDNPE ILDDFEKTLR FWLDRGVDGF RIDVAHGMAK
241 PPGLPDSPDL GIEVLHHRDD DPRFNHPNVH AIHRDIRTVI DEYPGAVTVG EVWVHDNARW
301 AEYLRPDELH LGFNFRLART EFDAAEIRDA VANSLAAAAL QNATPTWTLA NHDVGREVSR
361 YGGGEIGLRR AKAMAVVMLA LPGVVFLYNG QELGLPDVDL PDEVLQDPTW ERSGRTERGR
421 DGCRVPIPWS GNIPPFGFST CPDTWLPMPP EWAALTAEKQ RADAGSTLSF FRLALRLRRE
481 RNEFDGDVDW LAAPDDALIF RRHGGGLVCA LNAAERPLAL PAGEPILASA PLTDATLPPN
541 AAAWLV
//