LOCUS CCP45207.1 402 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Enhanced intracellular
survival protein Eis,GCN5-related N-acetyltransferase
protein.
ACCESSION AL123456-2485
PROTEIN_ID CCP45207.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene="eis"
/locus_tag="Rv2416c"
/note="Rv2416c, (MTCY253.04), len: 402 aa. Eis, enhanced
intracellular survival gene (see citations below).
Conserved hypothetical protein, contains GNAT
(Gcn5-related N-acetyltransferase) domain in N-terminal
part, similar to Q9F309|SCC80.10 hypothetical 44.7 KDA
protein from Streptomyces coelicolor (413 aa), FASTA
scores: opt: 382,E(): 1e-16, (31.45% identity in 407 aa
overlap); Q9K4F4|SCD66.23 conserved hypothetical protein
from Streptomyces coelicolor (418 aa), FASTA scores: opt:
238,E(): 1.3e-07, (36.5% identity in 364 aa overlap): and
Q54238|G1139577|ORF5 hypothetical protein from
Streptomyces griseus (416 aa), FASTA scores: opt: 237,
E(): 1.5e-07,(34.0 identity in 423 aa overlap). Start
changed since first submission (- 6 aa) (see Dahl et al.,
2001; Wei et al., 2000; Vetting et al. 2005)."
/db_xref="EnsemblGenomes-Gn:Rv2416c"
/db_xref="EnsemblGenomes-Tr:CCP45207"
/db_xref="GOA:P9WFK7"
/db_xref="InterPro:IPR000182"
/db_xref="InterPro:IPR016181"
/db_xref="InterPro:IPR022902"
/db_xref="InterPro:IPR025559"
/db_xref="InterPro:IPR036527"
/db_xref="InterPro:IPR041380"
/db_xref="PDB:3R1K"
/db_xref="PDB:3RYO"
/db_xref="PDB:3SXO"
/db_xref="PDB:3UY5"
/db_xref="PDB:4JD6"
/db_xref="PDB:5EBV"
/db_xref="PDB:5EC4"
/db_xref="PDB:5IV0"
/db_xref="PDB:5TVJ"
/db_xref="PDB:6B0U"
/db_xref="PDB:6B3T"
/db_xref="UniProtKB/Swiss-Prot:P9WFK7"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MTVTLCSPTE DDWPGMFLLA AASFTDFIGP ESATAWRTLV PTDGAVVVRD GAGPGSEVVG
61 MALYMDLRLT VPGEVVLPTA GLSFVAVAPT HRRRGLLRAM CAELHRRIAD SGYPVAALHA
121 SEGGIYGRFG YGPATTLHEL TVDRRFARFH ADAPGGGLGG SSVRLVRPTE HRGEFEAIYE
181 RWRQQVPGGL LRPQVLWDEL LAECKAAPGG DRESFALLHP DGYALYRVDR TDLKLARVSE
241 LRAVTADAHC ALWRALIGLD SMERISIITH PQDPLPHLLT DTRLARTTWR QDGLWLRIMN
301 VPAALEARGY AHEVGEFSTV LEVSDGGRFA LKIGDGRARC TPTDAAAEIE MDRDVLGSLY
361 LGAHRASTLA AANRLRTKDS QLLRRLDAAF ASDVPVQTAF EF
//