LOCUS       CCP45173.1               306 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Putative acetyl hydrolase
            MbtJ protein.
ACCESSION   AL123456-2451
PROTEIN_ID  CCP45173.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="mbtJ"
                     /gene_synonym="lipK"
                     /locus_tag="Rv2385"
                     /note="Rv2385, (MTCY253.36c), len: 306 aa. Putative
                     mbtJ,acetyl hydrolase (see citations below), showing some
                     similarity with various hydrolases including acetyl
                     hydrolases e.g. Q9ZBM4|MLCB1450.08|ML0314 putative
                     hydrolase/esterase from Mycobacterium leprae (335
                     aa),FASTA scores: opt: 449, E(): 6.7e-21, (33.85% identity
                     in 313 aa overlap); AAK47950|MT3591 Esterase from M.
                     tuberculosis strain CDC1551 (327 aa), FASTA scores: opt:
                     469, E(): 3.6e-22, (35% identity in 283 aa overlap);
                     Q9X8J4|SCE9.22 putative esterase from Streptomyces
                     coelicolor (266 aa), FASTA scores: opt: 430,E():
                     8.5e-20,(38% identity in 245 aa overlap); Q01109|BAH_STRHY
                     acetyl-hydrolase from Streptomyces hygroscopicus (299
                     aa),FASTA scores: opt: 420, E(): 4e-19, (35.1% identity in
                     265 aa overlap). Equivalent to AAK46748 from Mycobacterium
                     tuberculosis strain CDC1551 (327 aa) but shorter 21 aa.
                     Note that previously known as lipK."
                     /db_xref="EnsemblGenomes-Gn:Rv2385"
                     /db_xref="EnsemblGenomes-Tr:CCP45173"
                     /db_xref="GOA:Q79FE8"
                     /db_xref="InterPro:IPR013094"
                     /db_xref="InterPro:IPR029058"
                     /db_xref="UniProtKB/TrEMBL:Q79FE8"
BEGIN
        1 MVLRPITGAI PPDGPWGIWA SRRIIAGLMG TFGPSLAGTR VEQVNSVLPD GRRVVGEWVY
       61 GPHNNAINAG PGGGAIYYVH GSGYTMCSPR THRRLTSWLS SLTGLPVFSV DYRLAPRYRF
      121 PTAATDVRAA WDWLAHVCGL AAEHMVIAAD SAGGHLTVDM LLQPEVAARP PAAVVLFSPL
      181 IDLTFRLGAS RELQRPDPVV RADRAARSVA LYYTGVDPAH HRLALDVAGG PPLPPTLIQV
      241 GGAEILEADA RQLDADIRAA GGICELQVWP DQMHVFQALP RMTPEAAKAM TYVAQFIRST
      301 TARGDL
//