LOCUS       CCP45165.1                71 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Putative conserved protein
            MbtH protein.
ACCESSION   AL123456-2443
PROTEIN_ID  CCP45165.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="mbtH"
                     /locus_tag="Rv2377c"
                     /note="Rv2377c, (MT2445.1, MTCY27.03), len: 71 aa.
                     Putative mbtH, conserved protein with no function assigned
                     (see Quadri et al., 1998; De Voss et al., 1999), similar
                     to hypothetical proteins or proteins found in several gene
                     clusters for biosynthesis or transport of siderophores and
                     other nonribosomally synthesized peptides e.g.
                     Q9Z388|SCE8.11c putative small conserved hypothetical
                     protein from Streptomyces coelicolor (71 aa), FASTA
                     scores: opt: 345, E(): 1.4e-19, (68.2% identity in 66 aa
                     overlap); Q9F8V3|CUMB COUY protein (probably involved in
                     the biosynthesis of aminocoumarin antibiotic coumermycin
                     a(1)) (see Wang et al., 2000) from Streptomyces
                     rishiriensis (71 aa), FASTA scores: opt: 329, E():
                     2.2e-18, (63.2% identity in 68 aa overlap); Q9F5J2|SIM-CB
                     MBTH-like protein (probably protein involved in the
                     biosynthesis of aminocoumarin antibiotic coumermycin a(1))
                     from Streptomyces antibioticus (70 aa), FASTA scores: opt:
                     308,E(): 8.4e-17, (65.6% identity in 64 aa overlap);
                     Q9FB14 MBTH-like protein (involved in the biosynthesis of
                     the antitumor drug bleomycin) (see Du et al., 2000) from
                     Streptomyces verticillus FASTA scores: opt: 220, E():
                     8.8e-10, (41.2% identity in 68 aa overlap); etc."
                     /db_xref="EnsemblGenomes-Gn:Rv2377c"
                     /db_xref="EnsemblGenomes-Tr:CCP45165"
                     /db_xref="GOA:P9WIP5"
                     /db_xref="InterPro:IPR005153"
                     /db_xref="InterPro:IPR037407"
                     /db_xref="InterPro:IPR038020"
                     /db_xref="PDB:2KHR"
                     /db_xref="UniProtKB/Swiss-Prot:P9WIP5"
BEGIN
        1 MSTNPFDDDN GAFFVLVNDE DQHSLWPVFA DIPAGWRVVH GEASRAACLD YVEKNWTDLR
       61 PKSLRDAMVE D
//