LOCUS CCP45152.1 300 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Probable GTP-binding
protein Era protein.
ACCESSION AL123456-2430
PROTEIN_ID CCP45152.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene="era"
/gene_synonym="bex"
/locus_tag="Rv2364c"
/note="Rv2364c, (MT2433, MTCY27.16), len: 300 aa. Probable
era, GTP-binding protein, equivalent to
Q49768|ERA_MYCLE|ML0631|B1937_F3_102 GTP-binding protein
era homolog from Mycobacterium leprae (300 aa) FASTA
scores: opt: 1589, E(): 3.4e-88, (81.4% identity in 301 aa
overlap). Also highly similar to other GTP-binding
proteins e.g. Q9RDF2|ERA_STRCO|SCC77.06 from Streptomyces
coelicolor (317 aa), FASTA scores: opt: 1264, E():
1.1e-68, (64.0% identity in 306 aa overlap);
Q9KD52|ERA_BACHD|BH1367|BEX from Bacillus halodurans (304
aa), FASTA scores: opt: 869,(44.8% identity in 297 aa
overlap); Q9KIH7|ERA_LACLA|ERAL from Lactococcus lactis
(subsp. lactis) (Streptococcus lactis), and Lactococcus
lactis (subsp. cremoris) (Streptococcus cremoris) (303
aa), FASTA scores: opt: 781,E(): 9.4e-40, (40.25% identity
in 298 aa overlap); etc. Contains PS00017 ATP/GTP-binding
site motif A (P-loop). Belongs to the era/TRME family of
GTP-binding proteins, era subfamily. Note that previously
known as bex."
/db_xref="EnsemblGenomes-Gn:Rv2364c"
/db_xref="EnsemblGenomes-Tr:CCP45152"
/db_xref="GOA:P9WNK9"
/db_xref="InterPro:IPR004044"
/db_xref="InterPro:IPR005225"
/db_xref="InterPro:IPR005662"
/db_xref="InterPro:IPR006073"
/db_xref="InterPro:IPR009019"
/db_xref="InterPro:IPR015946"
/db_xref="InterPro:IPR027417"
/db_xref="InterPro:IPR030388"
/db_xref="UniProtKB/Swiss-Prot:P9WNK9"
/inference="protein motif:PROSITE:PS00017"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MTEFHSGFVC LVGRPNTGKS TLTNALVGAK VAITSTRPQT TRHAIRGIVH SDDFQIILVD
61 TPGLHRPRTL LGKRLNDLVR ETYAAVDVIG LCIPADEAIG PGDRWIVEQL RSTGPANTTL
121 VVIVTKIDKV PKEKVVAQLV AVSELVTNAA EIVPVSAMTG DRVDLLIDVL AAALPAGPAY
181 YPDGELTDEP EEVLMAELIR EAALQGVRDE LPHSLAVVID EVSPREGRDD LIDVHAALYV
241 ERDSQKGIVI GKGGARLREV GTAARSQIEN LLGTKVYLDL RVKVAKNWQR DPKQLGRLGF
//