LOCUS CCP45012.1 291 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Protein tyrosine kinase
transcriptional regulatory protein PtkA protein.
ACCESSION AL123456-2290
PROTEIN_ID CCP45012.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene="ptkA"
/locus_tag="Rv2232"
/note="Rv2232, (MTCY427.13), len: 291 aa. PtkA, protein
tyrosine kinase, similar to members of haloacid
dehalogenase-like family from several bacteria and to
putative phosphatases e.g. Q9I767 and AAK78398. Contains
N-terminal extension. FASTA scores: Q9I767 hypothetical
protein PA0065 (221 aa) opt: 439 E(): 3.2e-18; 38.679%
identity (40.196% ungapped) in 212 aa overlap;
>>tr|AAK78398 Predicted phosphatase, had family (216 aa)
opt: 427, E(): 1.5e-17; 34.762% identity (35.437%
ungapped) in 210 aa overlap. Replaces previous Rv2232 and
Rv2233. Predicted to be an outer membrane protein (See
Song et al.,2008)."
/db_xref="EnsemblGenomes-Gn:Rv2232"
/db_xref="EnsemblGenomes-Tr:CCP45012"
/db_xref="GOA:P9WPI9"
/db_xref="InterPro:IPR023198"
/db_xref="InterPro:IPR023214"
/db_xref="InterPro:IPR036412"
/db_xref="InterPro:IPR041492"
/db_xref="PDB:6F2X"
/db_xref="UniProtKB/Swiss-Prot:P9WPI9"
BEGIN
1 MSSPRERRPA SQAPRLSRRP PAHQTSRSSP DTTAPTGSGL SNRFVNDNGI VTDTTASGTN
61 CPPPPRAAAR RASSPGESPQ LVIFDLDGTL TDSARGIVSS FRHALNHIGA PVPEGDLATH
121 IVGPPMHETL RAMGLGESAE EAIVAYRADY SARGWAMNSL FDGIGPLLAD LRTAGVRLAV
181 ATSKAEPTAR RILRHFGIEQ HFEVIAGAST DGSRGSKVDV LAHALAQLRP LPERLVMVGD
241 RSHDVDGAAA HGIDTVVVGW GYGRADFIDK TSTTVVTHAA TIDELREALG V
//