LOCUS       CCP44990.1               515 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Probable aminopeptidase
            PepB protein.
ACCESSION   AL123456-2268
PROTEIN_ID  CCP44990.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="pepB"
                     /locus_tag="Rv2213"
                     /note="Rv2213, (MTCY190.24), len: 515 aa. Probable
                     pepB,leucine aminopeptidase, similar to many e.g.
                     SW:AMPA_ECOLI P11648 aminopeptidase a/I, (41.4% identity
                     in 309 aa overlap). Equivalent to Z98741|MLCB22_6
                     Mycobacterium leprae cosmid B22; Am (524 aa), FASTA
                     scores: opt: 2793,E(): 0; 83.1% identity in 522 aa
                     overlap. Contains PS00631 Cytosol aminopeptidase
                     signature, ntdaegrl. Conserved in M. tuberculosis, M.
                     leprae, M. bovis and M. avium paratuberculosis; predicted
                     to be essential for in vivo survival and pathogenicity
                     (See Ribeiro-Guimaraes and Pessolani, 2007)."
                     /db_xref="EnsemblGenomes-Gn:Rv2213"
                     /db_xref="EnsemblGenomes-Tr:CCP44990"
                     /db_xref="GOA:P9WHT3"
                     /db_xref="InterPro:IPR000819"
                     /db_xref="InterPro:IPR008283"
                     /db_xref="InterPro:IPR011356"
                     /db_xref="InterPro:IPR023042"
                     /db_xref="UniProtKB/Swiss-Prot:P9WHT3"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MTTEPGYLSP SVAVATSMPK RGVGAAVLIV PVVSTGEEDR PGAVVASAEP FLRADTVAEI
       61 EAGLRALDAT GASDQVHRLA VPSLPVGSVL TVGLGKPRRE WPADTIRCAA GVAARALNSS
      121 EAVITTLAEL PGDGICSATV EGLILGSYRF SAFRSDKTAP KDAGLRKITV LCCAKDAKKR
      181 ALHGAAVATA VATARDLVNT PPSHLFPAEF AKRAKTLSES VGLDVEVIDE KALKKAGYGG
      241 VIGVGQGSSR PPRLVRLIHR GSRLAKNPQK AKKVALVGKG ITFDTGGISI KPAASMHHMT
      301 SDMGGAAAVI ATVTLAARLR LPIDVIATVP MAENMPSATA QRPGDVLTQY GGTTVEVLNT
      361 DAEGRLILAD AIVRACEDKP DYLIETSTLT GAQTVALGTR IPGVMGSDEF RDRVAAISQR
      421 VGENGWPMPL PDDLKDDLKS TVADLANVSG QRFAGMLVAG VFLREFVAES VDWAHIDVAG
      481 PAYNTGSAWG YTPKGATGVP TRTMFAVLED IAKNG
//