LOCUS       CCP44735.1               425 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Mce-family protein Mce3A protein.
ACCESSION   AL123456-2013
PROTEIN_ID  CCP44735.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="mce3A"
                     /gene_synonym="mce3"
                     /locus_tag="Rv1966"
                     /note="Rv1966, (MTV051.04), len: 425 aa. Mce3A; belongs to
                     24-membered Mycobacterium tuberculosis Mce protein family
                     (see citations below), highly similar to Mycobacterium
                     tuberculosis proteins P72013|MCE1|Rv0169|MTCI28.09|mce1A
                     (454 aa); O07789|MCE2|Rv0589|MTCY19H5.33c|mce2A (404 aa);
                     etc. Also highly similar to others e.g.
                     AAD52105.1|AF113402_1|AF113402 mycobacterial cell entry
                     protein from Mycobacterium bovis BCG (454 aa);
                     NP_302656.1|NC_002677 putative cell invasion protein from
                     Mycobacterium leprae (441 aa); CAC12798.1|AL445327
                     putative secreted protein from Streptomyces coelicolor
                     (418 aa); etc. Contains a possible N-terminal signal
                     sequence or membrane anchor. Note that previously known as
                     mce3. The transcription of this CDS seems negatively
                     regulated by the product of Rv1963c|mce3R (see Santangelo
                     et al., 2002). Predicted to be an outer membrane protein
                     (See Song et al.,2008)."
                     /db_xref="EnsemblGenomes-Gn:Rv1966"
                     /db_xref="EnsemblGenomes-Tr:CCP44735"
                     /db_xref="GOA:L7N698"
                     /db_xref="InterPro:IPR003399"
                     /db_xref="InterPro:IPR005693"
                     /db_xref="InterPro:IPR024516"
                     /db_xref="UniProtKB/TrEMBL:L7N698"
BEGIN
        1 MRRGPGRHRL HDAWWTLILF AVIGVAVLVT AVSFTGSLRS TVPVTLAADR SGLVMDSGAK
       61 VMMRGVQVGR VAQIGRIEWA QNGASLRLEI DPDQIRYIPA NVEAQISATT AFGAKFVDLV
      121 MPQNPSRARL SAGAVLHSKN VSTEINTVFE NVVDLLNMID PLKLNAVLTA VADAVRGQGE
      181 RIGQATTDLN EVLEALNARG DTIGGNWRSL KNFTDTYDAA AQDILTILNA ASTTSATVVN
      241 HSTQLDALLL NAIGLSNAGT NLLGSSRDNL VGAADILAPT TSLLFKYNPE YTCFLQGAKW
      301 YLDNGGYAAW GGADGRTLQL DVALLFGNDP YVYPDNLPVV AAKGGPGGRP GCGPLPDATH
      361 NFPVRQLVTN TGWGTGLDIR PNPGIGHPCW ANYFPVTRAV PEPPSIRQCI PGPAIGPNPA
      421 AGEQP
//