LOCUS       CCP44317.1               247 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Probable fumarate reductase
            [iron-sulfur subunit] FrdB (fumarate dehydrogenase) (fumaric
            hydrogenase) protein.
ACCESSION   AL123456-1595
PROTEIN_ID  CCP44317.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="frdB"
                     /locus_tag="Rv1553"
                     /note="Rv1553, (MTCY48.12c), len: 247 aa. Probable
                     frdB,fumarate reductase, iron-sulfur subunit, highly
                     similar to others e.g. P00364|FRDB_ECOLI fumarate
                     reductase iron-sulfur protein from Escherichia coli strain
                     K12 (243 aa), FASTA scores: opt: 846, E(): 0, (50.0%
                     identity in 242 aa overlap); P20921|FRDB_PROVU fumarate
                     reductase iron-sulfur protein from Proteus vulgaris (245
                     aa); G64097 fumarate reductase iron-sulfur protein from
                     Haemophilus influenzae (276 aa); etc. Contains PS00198
                     4Fe-4S ferredoxins, iron-sulfur binding region signature.
                     Note that fumarate reductase forms part of an enzyme
                     complex containing four subunits: a flavoprotein
                     (Rv1552|frdA), an iron-sulfur (Rv1553|frdB), and two
                     hydrophobic anchor proteins (Rv1554|frdC and
                     Rv1555|frdD)."
                     /db_xref="EnsemblGenomes-Gn:Rv1553"
                     /db_xref="EnsemblGenomes-Tr:CCP44317"
                     /db_xref="GOA:P9WN89"
                     /db_xref="InterPro:IPR004489"
                     /db_xref="InterPro:IPR009051"
                     /db_xref="InterPro:IPR012675"
                     /db_xref="InterPro:IPR017896"
                     /db_xref="InterPro:IPR017900"
                     /db_xref="InterPro:IPR025192"
                     /db_xref="InterPro:IPR036010"
                     /db_xref="UniProtKB/Swiss-Prot:P9WN89"
                     /inference="protein motif:PROSITE:PS00198"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MMDRIVMEVS RYRPEIESAP TFQAYEVPLT REWAVLDGLT YIKDHLDGTL SFRWSCRMGI
       61 CGSSGMTING DPKLACATFL ADYLPGPVRV EPMRNFPVIR DLVVDISDFM AKLPSVKPWL
      121 VRHDEPPVED GEYRQTPAEL DAFKQFSMCI NCMLCYSACP VYALDPDFLG PAAIALGQRY
      181 NLDSRDQGAA DRRDVLAAAD GAWACTLVGE CSTACPKGVD PAGAIQRYKL TAATHALKKL
      241 LFPWGGG
//