LOCUS CCP44285.1 583 aa PRT BCT 27-FEB-2015 DEFINITION Mycobacterium tuberculosis H37Rv Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid- AMP synthase) protein. ACCESSION AL123456-1563 PROTEIN_ID CCP44285.1 SOURCE Mycobacterium tuberculosis H37Rv ORGANISM Mycobacterium tuberculosis H37Rv Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III., Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R., Devlin K., Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L., Oliver K., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J., Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. TITLE Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence JOURNAL Nature 393(6685), 537-544(1998). PUBMED 9634230 REMARK Erratum:[Nature 1998 Nov 12;396(6707):190] REFERENCE 2 AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T. TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002). PUBMED 12368430 REFERENCE 3 AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T. TITLE TubercuList--10 years after JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011). PUBMED 20980199 REFERENCE 4 (bases 1 to 4411529) AUTHORS Parkhill J. JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the Mycobacterium tuberculosis sequencing and mapping teams, Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail: parkhill@sanger.ac.uk REFERENCE 5 (bases 1 to 4411532) AUTHORS Lew J.M. JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva 4, SWITZERLAND COMMENT On or before Feb 1, 2013 this sequence version replaced gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250, gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756, gi:38490319, gi:41352785, gi:38490370, gi:41353971. Note: This annotation is from the TubercuList website, Release 26, Dec 2012 (URL: http://tuberculist.epfl.ch) (email: tuberculist@epfl.ch). FEATURES Qualifiers source /organism="Mycobacterium tuberculosis H37Rv" /strain="H37Rv" /mol_type="genomic DNA" /db_xref="taxon:83332" protein /transl_table=11 /gene="fadD25" /locus_tag="Rv1521" /note="Rv1521, (MTCY19G5.07), len: 583 aa. Probable fadD25,fatty-acid-AMP synthetase, highly similar to many e.g. P71495|U75685 acyl-CoA synthase from Mycobacterium bovis (582 aa), FASTA scores: opt: 2486, E(): 0, (63.4% identity in 584 aa overlap); NP_301232.1|NC_002677 acyl-CoA synthetase from Mycobacterium leprae (579 aa); etc. Also highly similar to others from Mycobacterium tuberculosis e.g. fadD24 (584 aa); fadD28 (580 aa); etc." /db_xref="EnsemblGenomes-Gn:Rv1521" /db_xref="EnsemblGenomes-Tr:CCP44285" /db_xref="GOA:P9WQ45" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR040097" /db_xref="InterPro:IPR042099" /db_xref="UniProtKB/Swiss-Prot:P9WQ45" /experiment="EXISTENCE: identified in proteomics study" BEGIN 1 MSVVESSLPG VLRERASFQP NDKALTFIDY ERSWDGVEET LTWSQLYRRT LNLAAQLREH 61 GSTGDRALIL APQSLDYVVS FIASLQAGIV AVPLSIPQGG AHDERTVSVF ADTAPAIVLT 121 ASSVVDNVVE YVQPQPGQNA PAVIEVDRLD LDARPSSGSR SAAHGHPDIL YLQYTSGSTR 181 TPAGVMVSNK NLFANFEQIM TSYYGVYGKV APPGSTVVSW LPFYHDMGFV LGLILPILAG 241 IPAVLTSPIG FLQRPARWIQ MLASNTLAFT AAPNFAFDLA SRKTKDEDME GLDLGGVHGI 301 LNGSERVQPV TLKRFIDRFA PFNLDPKAIR PSYGMAEATV YVATRKAGQP PKIVQFDPQK 361 LPDGQAERTE SDGGTPLVSY GIVDTQLVRI VDPDTGIERP AGTIGEIWVH GDNVAIGYWQ 421 KPEATERTFS ATIVNPSEGT PAGPWLRTGD SGFLSEGELF IMGRIKDLLI VYGRNHSPDD 481 IEATIQTISP GRCAAIAVSE HGAEKLVAII ELKKKDESDD EAAERLGFVK REVTSAISKS 541 HGLSVADLVL VSPGSIPITT SGKIRRAQCV ELYRQDEFTR LDA //