LOCUS CCP44232.1 542 aa PRT BCT 27-FEB-2015 DEFINITION Mycobacterium tuberculosis H37Rv Probable macrolide-transport ATP-binding protein ABC transporter protein. ACCESSION AL123456-1510 PROTEIN_ID CCP44232.1 SOURCE Mycobacterium tuberculosis H37Rv ORGANISM Mycobacterium tuberculosis H37Rv Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III., Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R., Devlin K., Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L., Oliver K., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J., Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. TITLE Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence JOURNAL Nature 393(6685), 537-544(1998). PUBMED 9634230 REMARK Erratum:[Nature 1998 Nov 12;396(6707):190] REFERENCE 2 AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T. TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002). PUBMED 12368430 REFERENCE 3 AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T. TITLE TubercuList--10 years after JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011). PUBMED 20980199 REFERENCE 4 (bases 1 to 4411529) AUTHORS Parkhill J. JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the Mycobacterium tuberculosis sequencing and mapping teams, Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail: parkhill@sanger.ac.uk REFERENCE 5 (bases 1 to 4411532) AUTHORS Lew J.M. JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva 4, SWITZERLAND COMMENT On or before Feb 1, 2013 this sequence version replaced gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250, gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756, gi:38490319, gi:41352785, gi:38490370, gi:41353971. Note: This annotation is from the TubercuList website, Release 26, Dec 2012 (URL: http://tuberculist.epfl.ch) (email: tuberculist@epfl.ch). FEATURES Qualifiers source /organism="Mycobacterium tuberculosis H37Rv" /strain="H37Rv" /mol_type="genomic DNA" /db_xref="taxon:83332" protein /transl_table=11 /locus_tag="Rv1473" /note="Rv1473, (MTV007.20), len: 542 aa. Possible macrolide-transport ATP-binding protein ABC transporter (see citation below), possibly in EF-3 subfamily. Similar to many ABC-transporters e.g. D90909_48|YHES_HAEIN from Synechocystis sp. strain PCC6803 (574 aa), FASTA scores: opt: 870, E(): 0, (33.3% identity in 525 aa overlap); P44808|YHES_HAEIN from Haemophilus influenzae (638 aa),FASTA scores: opt: 706, E(): 0, (33.7% identity in 517 aa overlap); etc. Contains two PS00017 ATP/GTP-binding site motif A (P-loop), and two PS00211 ABC transporter family signatures. Belongs to the ATP-binding transport protein family (ABC transporters)." /db_xref="EnsemblGenomes-Gn:Rv1473" /db_xref="EnsemblGenomes-Tr:CCP44232" /db_xref="GOA:O53164" /db_xref="InterPro:IPR003439" /db_xref="InterPro:IPR003593" /db_xref="InterPro:IPR017871" /db_xref="InterPro:IPR027417" /db_xref="InterPro:IPR032781" /db_xref="UniProtKB/TrEMBL:O53164" /inference="protein motif:PROSITE:PS00017" /inference="protein motif:PROSITE:PS00211" /experiment="EXISTENCE: identified in proteomics study" BEGIN 1 MITATDLEVR AGARILLAPD GPDLRVQPGD RIGLVGRNGA GKTTTLRILA GEVEPYAGSV 61 TRAGEIGYLP QDPKVGDLDV LARDRVLSAR GLDVLLTDLE KQQALMAEVA DEDERDRAIR 121 RYGQLEERFV ALGGYGAESE AGRICASLGL PERVLTQRLR TLSGGQRRRV ELARILFAAS 181 ESGAGNSTTL LLDEPTNHLD ADSLGWLRDF LRLHTGGLVV ISHNVDLVAD VVNKVWFLDA 241 VRGQVDVYNM GWQRYVDARA TDEQRRIRER ANAERKAAAL RAQAAKLGAK ATKAVAAQNM 301 LRRADRMMAA LDEERVADKV ARIKFPTPAA CGRTPLVANG LGKTYGSLEV FTGVDLAIDR 361 GSRVVILGLN GAGKTTLLRL LAGVEQPDTG VLEPGYGLRI GYFAQEHDTL DNDATVWENV 421 RHAAPDAGEQ DLRGLLGAFM FTGPQLEQPA GTLSGGEKTR LALAGLVAST ANVLLLDEPT 481 NNLDPASREQ VLDALRSYRG AVVLVTHDPG AAAALGPQRV VLLPDGTEDY WSDEYRDLIE 541 LA //