LOCUS CCP43962.1 597 aa PRT BCT 27-FEB-2015 DEFINITION Mycobacterium tuberculosis H37Rv Probable fatty-acid-CoA ligase FadD6 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) protein. ACCESSION AL123456-1240 PROTEIN_ID CCP43962.1 SOURCE Mycobacterium tuberculosis H37Rv ORGANISM Mycobacterium tuberculosis H37Rv Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III., Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R., Devlin K., Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L., Oliver K., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J., Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. TITLE Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence JOURNAL Nature 393(6685), 537-544(1998). PUBMED 9634230 REMARK Erratum:[Nature 1998 Nov 12;396(6707):190] REFERENCE 2 AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T. TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002). PUBMED 12368430 REFERENCE 3 AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T. TITLE TubercuList--10 years after JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011). PUBMED 20980199 REFERENCE 4 (bases 1 to 4411529) AUTHORS Parkhill J. JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the Mycobacterium tuberculosis sequencing and mapping teams, Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail: parkhill@sanger.ac.uk REFERENCE 5 (bases 1 to 4411532) AUTHORS Lew J.M. JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva 4, SWITZERLAND COMMENT On or before Feb 1, 2013 this sequence version replaced gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250, gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756, gi:38490319, gi:41352785, gi:38490370, gi:41353971. Note: This annotation is from the TubercuList website, Release 26, Dec 2012 (URL: http://tuberculist.epfl.ch) (email: tuberculist@epfl.ch). FEATURES Qualifiers source /organism="Mycobacterium tuberculosis H37Rv" /strain="H37Rv" /mol_type="genomic DNA" /db_xref="taxon:83332" protein /transl_table=11 /gene="fadD6" /locus_tag="Rv1206" /note="Rv1206, (MTCI364.18), len: 597 aa. Probable fadD6,fatty-acid-CoA synthetase, highly similar to several e.g. NP_251583.1|NC_002516 probable very-long-chain acyl-CoA synthetase from Pseudomonas aeruginosa (608 aa); Q60714 mouse fatty acid transport protein fatp (646 aa), FASTA scores: opt:712, E(): 0, (36.8% identity in 600 aa overlap); etc. Contains PS00017 ATP/GTP-binding site motif A (P-loop), and PS00455 Putative AMP-binding domain signature. Belongs to the ATP-dependent AMP-binding enzyme family." /db_xref="EnsemblGenomes-Gn:Rv1206" /db_xref="EnsemblGenomes-Tr:CCP43962" /db_xref="GOA:O05307" /db_xref="InterPro:IPR000873" /db_xref="InterPro:IPR020845" /db_xref="InterPro:IPR025110" /db_xref="InterPro:IPR030310" /db_xref="InterPro:IPR042099" /db_xref="UniProtKB/TrEMBL:O05307" /inference="protein motif:PROSITE:PS00455" /inference="protein motif:PROSITE:PS00017" /experiment="EXISTENCE: identified in proteomics study" BEGIN 1 MSDYYGGAHT TVRLIDLATR MPRVLADTPV IVRGAMTGLL ARPNSKASIG TVFQDRAARY 61 GDRVFLKFGD QQLTYRDANA TANRYAAVLA ARGVGPGDVV GIMLRNSPST VLAMLATVKC 121 GAIAGMLNYH QRGEVLAHSL GLLDAKVLIA ESDLVSAVAE CGASRGRVAG DVLTVEDVER 181 FATTAPATNP ASASAVQAKD TAFYIFTSGT TGFPKASVMT HHRWLRALAV FGGMGLRLKG 241 SDTLYSCLPL YHNNALTVAV SSVINSGATL ALGKSFSASR FWDEVIANRA TAFVYIGEIC 301 RYLLNQPAKP TDRAHQVRVI CGNGLRPEIW DEFTTRFGVA RVCEFYAASE GNSAFINIFN 361 VPRTAGVSPM PLAFVEYDLD TGDPLRDASG RVRRVPDGEP GLLLSRVNRL QPFDGYTDPV 421 ASEKKLVRNA FRDGDCWFNT GDVMSPQGMG HAAFVDRLGD TFRWKGENVA TTQVEAALAS 481 DQTVEECTVY GVQIPRTGGR AGMAAITLRA GAEFDGQALA RTVYGHLPGY ALPLFVRVVG 541 SLAHTTTFKS RKVELRNQAY GADIEDPLYV LAGPDEGYVP YYAEYPEEVS LGRRPQG //