LOCUS CCP43949.1 473 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Probable fatty-acid-CoA
ligase FadD36 (fatty-acid-CoA synthetase) (fatty-acid-
CoA synthase) protein.
ACCESSION AL123456-1227
PROTEIN_ID CCP43949.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene="fadD36"
/locus_tag="Rv1193"
/note="Rv1193, (MTCI364.05), len: 473 aa. Probable
fadD36,fatty-acid-CoA synthetase, highly similar to
Q50017|U15181 4-coumarate-CoA ligase from Mycobacterium
leprae (476 aa),FASTA scores: opt: 2594, E(): 0, (81.3%
identity in 476 aa overlap). Also highly similar to others
e.g. CAB86109.1|AL163003 putative fatty acid synthase from
Streptomyces coelicolor (485 aa); LCFA_ECOLI|P29212
long-chain-fatty-acid--CoA ligase from Escherichia coli
(561 aa), FASTA scores: opt: 605, E(): 8.4e-30, (33.0%
identity in 364 aa overlap); etc. Contains PS00455
Putative AMP-binding domain signature. Belongs to the
ATP-dependent AMP-binding enzyme family."
/db_xref="EnsemblGenomes-Gn:Rv1193"
/db_xref="EnsemblGenomes-Tr:CCP43949"
/db_xref="GOA:O05295"
/db_xref="InterPro:IPR000873"
/db_xref="InterPro:IPR020845"
/db_xref="InterPro:IPR025110"
/db_xref="InterPro:IPR042099"
/db_xref="UniProtKB/TrEMBL:O05295"
/inference="protein motif:PROSITE:PS00455"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MLLASLNPAV VSAADIADAV RIDGDVLSRS DLVGAATSVA ERVAGAHRVA VLATPTASTV
61 LAITGCLIAG VPVVPVPADV GVTERRHMLT DSGVQAWLGP LPDDPAGLPH IPVRTHARSW
121 HRYPEPSPGA IAMVVYTSGT TGPPKGVQLS RRAIAADLDA LAEAWQWTAE DVLVHGLPLY
181 HVHGLVLGLL GSLRFGNRFV HTGKPTPAGY AQACYEAHGT LFFGVPTVWS RVAADQAAAG
241 ALKPARLLVS GSAALPVPVF DKLVQLTGHR PVERYGASES LITLSTRADG ERRPGWVGLP
301 LAGVQTRLVD DDGGEVPHDG ETVGKLQVRG PTLFDGYLNQ PDATAAAFDA DSWYRTGDVA
361 VVDGSGMHRI VGRESVDLIK SGGYRVGAGE IETVLLGHPD VAEAAVVGVP DDDLGQRIVA
421 YVVGSANVDA DGLINFVAQQ LSVHKRPREV RIVDALPRNA LGKVLKKQLL SEG
//