LOCUS       CCP43885.1               393 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Probable methylcitrate
            synthase PrpC protein.
ACCESSION   AL123456-1163
PROTEIN_ID  CCP43885.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="prpC"
                     /gene_synonym="gltA1"
                     /locus_tag="Rv1131"
                     /note="Rv1131, (MTCY22G8.20), len: 393 aa. Probable
                     prpC,methylcitrate synthase (MCS) (previously known as
                     gltA1) ,highly similar to CISY_MYCSM|P26491 citrate
                     synthase from Mycobacterium smegmatis (375 aa), FASTA
                     scores: opt:1942,E(): 0, (80.0% identity in 375 aa
                     overlap). Also similar to two other M. tuberculosis
                     citrate synthases,Rv0896c|MTCY31.24|gltA2 (431 aa), FASTA
                     score: (33.1% identity in 381 aa overlap) and
                     Rv0889|MTCY31.17c|citA (373 aa), FASTA score: (31.8%
                     identity in 371 aa overlap). Contains PS00480 Citrate
                     synthase signature. Belongs to the citrate synthase
                     family."
                     /db_xref="EnsemblGenomes-Gn:Rv1131"
                     /db_xref="EnsemblGenomes-Tr:CCP43885"
                     /db_xref="GOA:I6Y9Q3"
                     /db_xref="InterPro:IPR002020"
                     /db_xref="InterPro:IPR011278"
                     /db_xref="InterPro:IPR016142"
                     /db_xref="InterPro:IPR016143"
                     /db_xref="InterPro:IPR019810"
                     /db_xref="InterPro:IPR024176"
                     /db_xref="InterPro:IPR036969"
                     /db_xref="PDB:3HWK"
                     /db_xref="UniProtKB/Swiss-Prot:I6Y9Q3"
                     /inference="protein motif:PROSITE:PS00480"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MTGPLAAARS VAATKSMTAP TVDERPDIKK GLAGVVVDTT AISKVVPQTN SLTYRGYPVQ
       61 DLAARCSFEQ VAFLLWRGEL PTDAELALFS QRERASRRVD RSMLSLLAKL PDNCHPMDVV
      121 RTAISYLGAE DPDEDDAAAN RAKAMRMMAV LPTIVAIDMR RRRGLPPIAP HSGLGYAQNF
      181 LHMCFGEVPE TAVVSAFEQS MILYAEHGFN ASTFAARVVT STQSDIYSAV TGAIGALKGR
      241 LHGGANEAVM HDMIEIGDPA NAREWLRAKL ARKEKIMGFG HRVYRHGDSR VPTMKRALER
      301 VGTVRDGQRW LDIYQVLAAE MASATGILPN LDFPTGPAYY LMGFDIASFT PIFVMSRITG
      361 WTAHIMEQAT ANALIRPLSA YCGHEQRVLP GTF
//