LOCUS CCP43757.1 519 aa PRT BCT 27-FEB-2015 DEFINITION Mycobacterium tuberculosis H37Rv Methionyl-tRNA synthetase MetS (MetRS) (methionine--tRNA ligase) protein. ACCESSION AL123456-1035 PROTEIN_ID CCP43757.1 SOURCE Mycobacterium tuberculosis H37Rv ORGANISM Mycobacterium tuberculosis H37Rv Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III., Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R., Devlin K., Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L., Oliver K., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J., Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. TITLE Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence JOURNAL Nature 393(6685), 537-544(1998). PUBMED 9634230 REMARK Erratum:[Nature 1998 Nov 12;396(6707):190] REFERENCE 2 AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T. TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002). PUBMED 12368430 REFERENCE 3 AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T. TITLE TubercuList--10 years after JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011). PUBMED 20980199 REFERENCE 4 (bases 1 to 4411529) AUTHORS Parkhill J. JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the Mycobacterium tuberculosis sequencing and mapping teams, Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail: parkhill@sanger.ac.uk REFERENCE 5 (bases 1 to 4411532) AUTHORS Lew J.M. JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva 4, SWITZERLAND COMMENT On or before Feb 1, 2013 this sequence version replaced gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250, gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756, gi:38490319, gi:41352785, gi:38490370, gi:41353971. Note: This annotation is from the TubercuList website, Release 26, Dec 2012 (URL: http://tuberculist.epfl.ch) (email: tuberculist@epfl.ch). FEATURES Qualifiers source /organism="Mycobacterium tuberculosis H37Rv" /strain="H37Rv" /mol_type="genomic DNA" /db_xref="taxon:83332" protein /transl_table=11 /gene="metS" /locus_tag="Rv1007c" /note="Rv1007c, (MTCI237.24), len: 519 aa. metS (MetG),methionyl-tRNA synthetase, similar to many e.g. SYM_BACSU|P37465 methionyl-tRNA synthetase from Bacillus subtilus (664 aa), FASTA scores: opt: 1506, E(): 0, (44.9% identity in 492 aa overlap); similar to other Mycobacterium tuberculosis tRNA synthases e.g. Rv2448c, Rv1536, Rv0041. Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature. Belongs to class-I aminoacyl-tRNA synthetase family. Strong, to cysteinyl-tRNA synthetase." /db_xref="EnsemblGenomes-Gn:Rv1007c" /db_xref="EnsemblGenomes-Tr:CCP43757" /db_xref="GOA:P9WFU5" /db_xref="InterPro:IPR001412" /db_xref="InterPro:IPR009080" /db_xref="InterPro:IPR014729" /db_xref="InterPro:IPR014758" /db_xref="InterPro:IPR015413" /db_xref="InterPro:IPR023457" /db_xref="InterPro:IPR033911" /db_xref="InterPro:IPR041872" /db_xref="PDB:6AX8" /db_xref="UniProtKB/Swiss-Prot:P9WFU5" /inference="protein motif:PROSITE:PS00178" /experiment="EXISTENCE: identified in proteomics study" BEGIN 1 MKPYYVTTAI AYPNAAPHVG HAYEYIATDA IARFKRLDRY DVRFLTGTDE HGLKVAQAAA 61 AAGVPTAALA RRNSDVFQRM QEALNISFDR FIRTTDADHH EASKELWRRM SAAGDIYLDN 121 YSGWYSVRDE RFFVESETQL VDGTRLTVET GTPVTWTEEQ TYFFRLSAYT DKLLAHYHAN 181 PDFIAPETRR NEVISFVSGG LDDLSISRTS FDWGVQVPEH PDHVMYVWVD ALTNYLTGAG 241 FPDTDSELFR RYWPADLHMI GKDIIRFHAV YWPAFLMSAG IELPRRIFAH GFLHNRGEKM 301 SKSVGNIVDP VALAEALGVD QVRYFLLREV PFGQDGSYSD EAIVTRINTD LANELGNLAQ 361 RSLSMVAKNL DGRVPNPGEF ADADAALLAT ADGLLERVRG HFDAQAMHLA LEAIWLMLGD 421 ANKYFSVQQP WVLRKSESEA DQARFRTTLY VTCEVVRIAA LLIQPVMPES AGKILDLLGQ 481 APNQRSFAAV GVRLTPGTAL PPPTGVFPRY QPPQPPEGK //