LOCUS CCP43734.1 181 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Possible pterin-4-alpha-
carbinolamine dehydratase MoaB2 (PHS) (4-alpha-hydroxy-
tetrahydropterin dehydratase) (pterin-4-a-carbinolamine
dehydratase) (phenylalanine hydroxylase-stimulating protein)
(PHS) (pterin carbinolamine dehydratase) (PCD) protein.
ACCESSION AL123456-1012
PROTEIN_ID CCP43734.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene="moaB2"
/locus_tag="Rv0984"
/note="Rv0984, (MTV044.12), len: 181 aa. Possible
moaB2,pterin-4-alpha-carbinolamine dehydratase, highly
similar to NP_301253.1|NC_002677 putative molybdenum
cofactor biosynthesis protein from Mycobacterium leprae
(181 aa),FASTA score: (92.3% identity in 181 aa overlap).
Also similar to others e.g. CAB59675.1|AL132674 molybdenum
cofactor biosynthesis protein from Streptomyces coelicolor
(179 aa); Q56208|MOCB_SYNP7 molybdenum cofactor
biosynthesis protein CB from Synechococcus sp. (319
aa),FASTA score: (37.3% identity in 142 aa overlap);
C-terminus of NP_197599.1|NC_003076 molybdopterin
biosynthesis CNX1 protein from Arabidopsis thaliana (670
aa); etc. Also similar to Rv0865|MOG from Mycobacterium
tuberculosis (160 aa); and other mog proteins e.g.
CAC39235.1|AJ312124 Mog protein from Eubacterium
acidaminophilum (162 aa). Could belong to the
pterin-4-alpha-carbinolamine dehydratase family.
Alternative start codon has been suggested in position
1100508."
/db_xref="EnsemblGenomes-Gn:Rv0984"
/db_xref="EnsemblGenomes-Tr:CCP43734"
/db_xref="GOA:O53897"
/db_xref="InterPro:IPR001453"
/db_xref="InterPro:IPR036425"
/db_xref="UniProtKB/TrEMBL:O53897"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MKVAAQCSKL GYTVAPMEQR AELVVGRALV VVVDDRTAHG DEDHSGPLVT ELLTEAGFVV
61 DGVVAVSADE VEIRNALNTA VIGGVDLVVS VGGTGVTPRD VTPEATRDIL DREILGIAEA
121 IRASGLSAGI VDAGLSRGLA GVSGSTLVVN LAGSRYAVRD GMATLNPLAA QIIGQLSSLE
181 I
//