LOCUS CCP43608.1 720 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Probable fatty oxidation
protein FadB protein.
ACCESSION AL123456-886
PROTEIN_ID CCP43608.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene="fadB"
/locus_tag="Rv0860"
/note="Rv0860, (MTV043.53), len: 720 aa. Probable
fadB,fatty oxidation protein, equivalent to
NP_302422.1|NC_002677 putative fatty oxidation complex
alpha subunit from Mycobacterium leprae (714 aa). Also
highly similar to others and various proteins involved in
fatty acid metabolism, e.g. T35429 probable fatty
oxidation protein from Streptomyces coelicolor (733 aa);
NP_250428.1|NC_002516 probable 3-hydroxyacyl-CoA
dehydrogenase from Pseudomonas aeruginosa (714 aa);
NP_418895.1|NC_002696 fatty oxidation complex alpha
subunit from Caulobacter crescentus (709 aa);
P40939|ECHA_HUMAN trifunctional enzyme alpha subunit
[includes: long-chain enoyl-CoA hydratase ; long chain
3-hydroxyacyl-CoA dehydrogenase ] from Homo sapiens (763
aa), FASTA scores: opt: 1176, E(): 0, (32.4% identity in
722 aa overlap); P21177|FADB_ECOLI fatty oxidation complex
alpha subunit [includes: enoyl-CoA hydratase;
delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase;
3-hydroxyacyl-CoA dehydrogenase; 3- hydroxybutyryl-CoA
epimerase] from Escherichia coli strain K12 (729 aa),
FASTA scores: opt: 873, E(): 0, (33.6% identity in 693 aa
overlap); etc."
/db_xref="EnsemblGenomes-Gn:Rv0860"
/db_xref="EnsemblGenomes-Tr:CCP43608"
/db_xref="GOA:O53872"
/db_xref="InterPro:IPR001753"
/db_xref="InterPro:IPR006108"
/db_xref="InterPro:IPR006176"
/db_xref="InterPro:IPR008927"
/db_xref="InterPro:IPR029045"
/db_xref="InterPro:IPR036291"
/db_xref="PDB:4B3H"
/db_xref="PDB:4B3I"
/db_xref="PDB:4B3J"
/db_xref="UniProtKB/TrEMBL:O53872"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MPDNTIQWDK DADGIVTLTM DDPSGSTNVM NEAYIESMGK AVDRLVAEKD SITGVVVASA
61 KKTFFAGGDV KTMIQARPED AGDVFNTVET IKRQLRTLET LGKPVVAAIN GAALGGGLEI
121 ALACHHRIAA DVKGSQLGLP EVTLGLLPGG GGVTRTVRMF GIQNAFVSVL AQGTRFKPAK
181 AKEIGLVDEL VATVEELVPA AKAWIKEELK ANPDGAGVQP WDKKGYKMPG GTPSSPGLAA
241 ILPSFPSNLR KQLKGAPMPA PRAILAAAVE GAQVDFDTAS RIESRYFASL VTGQVAKNMM
301 QAFFFDLQAI NAGGSRPEGI GKTPIKRIGV LGAGMMGAGI AYVSAKAGYE VVLKDVSLEA
361 AAKGKGYSEK LEAKALERGR TTQERSDALL ARITPTADAA DFKGVDFVIE AVFENQELKH
421 KVFGEIEDIV EPNAILGSNT STLPITGLAT GVKRQEDFIG IHFFSPVDKM PLVEIIKGEK
481 TSDEALARVF DYTLAIGKTP IVVNDSRGFF TSRVIGTFVN EALAMLGEGV EPASIEQAGS
541 QAGYPAPPLQ LSDELNLELM HKIAVATRKG VEDAGGTYQP HPAEAVVEKM IELGRSGRLK
601 GAGFYEYADG KRSGLWPGLR ETFKSGSSQP PLQDMIDRML FAEALETQKC LDEGVLTSTA
661 DANIGSIMGI GFPPWTGGSA QFIVGYSGPA GTGKAAFVAR ARELAAAYGD RFLPPESLLS
//