LOCUS CCP43556.1 527 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Amidophosphoribosyltransferase
PurF (glutamine phosphoribosylpyrophosphate amidotransferase)
(ATASE) (gpatase) protein.
ACCESSION AL123456-834
PROTEIN_ID CCP43556.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene="purF"
/locus_tag="Rv0808"
/note="Rv0808, (MTCY07H7A.01c), len: 527 aa.
PurF,amidophosphoribosyltransferase, equivalent to
MLCB5_32|Q50028|PURF from Mycobacterium leprae (556
aa),FASTA scores: (91.3% identity in 518 aa overlap); and
CAB96578.1|AJ278609 phosphoribosyl pyrophosphate
amidotransferase from Mycobacterium smegmatis (511 aa)(see
citation below). Also highly similar to others e.g.
BAA89439.1|AB003158 amidophosphoribosyl transferase from
Corynebacterium ammoniagenes (490 aa); P00497|PUR1_BACSU
amidophosphoribosyltransferase precursor from Bacillus
subtilis (476 aa), FASTA scores: opt: 1412, E(): 0, (46.2%
identity in 470 aa overlap); etc. Contains PS00103
Purine/pyrimidine phosphoribosyl transferases signature.
Belongs to the purine/pyrimidine phosphoribosyltransferase
family."
/db_xref="EnsemblGenomes-Gn:Rv0808"
/db_xref="EnsemblGenomes-Tr:CCP43556"
/db_xref="GOA:P9WHQ7"
/db_xref="InterPro:IPR000836"
/db_xref="InterPro:IPR005854"
/db_xref="InterPro:IPR017932"
/db_xref="InterPro:IPR029055"
/db_xref="InterPro:IPR029057"
/db_xref="InterPro:IPR035584"
/db_xref="UniProtKB/Swiss-Prot:P9WHQ7"
/inference="protein motif:PROSITE:PS00103"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MAVDSDYVTD RAAGSRQTVT GQQPEQDLNS PREECGVFGV WAPGEDVAKL TYYGLYALQH
61 RGQEAAGIAV ADGSQVLVFK DLGLVSQVFD EQTLAAMQGH VAIGHCRYST TGDTTWENAQ
121 PVFRNTAAGT GVALGHNGNL VNAAALAARA RDAGLIATRC PAPATTDSDI LGALLAHGAA
181 DSTLEQAALD LLPTVRGAFC LTFMDENTLY ACRDPYGVRP LSLGRLDRGW VVASETAALD
241 IVGASFVRDI EPGELLAIDA DGVRSTRFAN PTPKGCVFEY VYLARPDSTI AGRSVHAARV
301 EIGRRLAREC PVEADLVIGV PESGTPAAVG YAQESGVPYG QGLMKNAYVG RTFIQPSQTI
361 RQLGIRLKLN PLKEVIRGKR LIVVDDSIVR GNTQRALVRM LREAGAVELH VRIASPPVKW
421 PCFYGIDFPS PAELIANAVE NEDEMLEAVR HAIGADTLGY ISLRGMVAAS EQPTSRLCTA
481 CFDGKYPIEL PRETALGKNV IEHMLANAAR GAALGELAAD DEVPVGR
//