LOCUS       CCP43505.1               485 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Possible two component
            system response sensor kinase membrane associated PhoR
            protein.
ACCESSION   AL123456-783
PROTEIN_ID  CCP43505.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="phoR"
                     /locus_tag="Rv0758"
                     /note="Rv0758, (MTCY369.03), len: 485 aa. Possible
                     phoR,two component system response phosphate sensor kinase
                     membrane-associated, highly similar to various sensor
                     kinases e.g. CAC32361.1|AL583945 putative two component
                     system histidine kinase from Streptomyces coelicolor (524
                     aa); NP_349365.1|NC_003030 Membrane-associated sensory
                     histidine kinase with HAMP domain from Clostridium
                     acetobutylicum (482 aa); and similar to phoP proteins e.g.
                     NP_372216.1|NC_002758 alkaline phosphatase synthesis
                     sensor protein from Staphylococcus aureus (554 aa);
                     P23545|PHOR_BACSU alkaline phosphatase synthesis sensor
                     from Bacillus subtilis (579 aa), FASTA scores: opt:
                     515,E(): 1.9e-25, (40.0% identity in 230 aa overlap); etc.
                     Also similar to proteins from Mycobacterium tuberculosis
                     e.g. MTCY20G9.16 FASTA scores: (34.5% identity in 264 aa
                     overlap), MTU88959_2 (509 aa), MTCY10G2_17, etc."
                     /db_xref="EnsemblGenomes-Gn:Rv0758"
                     /db_xref="EnsemblGenomes-Tr:CCP43505"
                     /db_xref="GOA:P71815"
                     /db_xref="InterPro:IPR003594"
                     /db_xref="InterPro:IPR003660"
                     /db_xref="InterPro:IPR003661"
                     /db_xref="InterPro:IPR004358"
                     /db_xref="InterPro:IPR005467"
                     /db_xref="InterPro:IPR036097"
                     /db_xref="InterPro:IPR036890"
                     /db_xref="PDB:5UKV"
                     /db_xref="PDB:5UKY"
                     /db_xref="UniProtKB/TrEMBL:P71815"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MARHLRGRLP LRVRLVAATL ILVATGLVAS GIAVTSMLQH RLTSRIDRVL LEEAQIWAQI
       61 TLPLAPDPYP GHNPDRPPSR FYVRVISPDG QSYTALNDNT AIPAVPANND VGRHPTTLPS
      121 IGGSKTLWRA VSVRASDGYL TTVAIDLADV RSTVRSLVLL QVGIGSAVLV VPGVAGYAVV
      181 RRSLRPLAEF EQTAAAIGAG QLDRRVPQWH PRTEVGRLSL ALNGMLAQIQ RAVASAESSA
      241 EKARDSEDRM RQFITDASHE LRTPLTTIRG FAELYRQGAA RDVGMLLSRI ESEASRMGLL
      301 VDDLLLLARL DAHRPLELCR VDLLALASDA AHDARAMDPK RRITLEVLDG PGTPEVLGDE
      361 SRLRQVLRNL VANAIQHTPE SADVTVRVGT EGDDAILEVA DDGPGMSQED ALRVFERFYR
      421 ADSSRARASG GTGLGLSIVD SLVAAHGGAV TVTTALGEGC CFRVSLPRVS DVDQLSLTPV
      481 VPGPP
//