LOCUS       CCP43412.1               637 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Possible hydrolase protein.
ACCESSION   AL123456-690
PROTEIN_ID  CCP43412.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /locus_tag="Rv0669c"
                     /note="Rv0669c, (MTCI376.05), len: 637 aa. Possible
                     hydrolase, highly similar to various hydrolases
                     (N-terminus shorter) e.g. BAA88409.1|AB028646 alkaline
                     ceramidase from Pseudomonas aeruginosa (670 aa,) FASTA
                     scores: opt: 1490,E(): 0, (41.2% identity in 651 aa
                     overlap); NP_063946.1|NM_019893 mitochondrial ceramidase
                     from Homo sapiens (761 aa); P_446098.1|NM_053646
                     N-acylsphingosine amidohydrolase 2 from Rattus norvegicus
                     (761 aa); BAB09641.1|AB016885 neutral ceramidase from
                     Arabidopsis thaliana (705 aa); etc. Contains PS00017
                     ATP/GTP-binding site motif A (P-loop)."
                     /db_xref="EnsemblGenomes-Gn:Rv0669c"
                     /db_xref="EnsemblGenomes-Tr:CCP43412"
                     /db_xref="GOA:O06769"
                     /db_xref="InterPro:IPR006823"
                     /db_xref="InterPro:IPR031329"
                     /db_xref="InterPro:IPR031331"
                     /db_xref="InterPro:IPR038445"
                     /db_xref="UniProtKB/Swiss-Prot:O06769"
                     /inference="protein motif:PROSITE:PS00017"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MLSVGRGIAD ITGEAADCGM LGYGKSDQRT AGIHQRLRSR AFVFRDDSQD GDARLLLIVA
       61 ELPLPMQNVN EEVLRRLADL YGDTYSEQNT LITATHTHAG PGGYCGYLLY NLTTSGFRPA
      121 TFAAIVDGIV ESVEHAHADV APAEVSLSHG ELYGASINRS PSAFDRNPPA DKAFFPKRVD
      181 PHTTLVRIDR GEATVGVIHF FATHGTSMTN RNHLISGDNK GFAAYHWERT VGGADYLAGQ
      241 PDFIAAFAQT NPGDMSPNVD GPLSPEAPPD REFDNTRRTG LCQFEDAFTQ LSGATPIGAG
      301 IDARFTYVDL GSVLVRGEYT PDGEERRTGR PMFGAGAMAG TDEGPGFHGF RQGRNPFWDR
      361 LSRAMYRLAR PTAAAQAPKG IVMPARLPNR IHPFVQEIVP VQLVRIGRLY LIGIPGEPTI
      421 VAGLRLRRMV ASIVGADLAD VLCVGYTNAY IHYVTTPEEY LEQRYEGGST LFGRWELCAL
      481 MQTVAELAEA MRDGRPVTLG RRPRPTRELS WVRGAPADAG SFGAVIAEPS ATYRPGQAVE
      541 AVFVSALPNN DLRRGGTYLE VVRREGASWV RIADDGDWAT SFRWQRQGRA GSHVSIRWDV
      601 PGDTTPGQYR IVHHGTARDR NGMLTAFSAT TREFTVV
//