LOCUS CCP43177.1 256 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Possible conserved transmembrane
protein protein.
ACCESSION AL123456-455
PROTEIN_ID CCP43177.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/locus_tag="Rv0446c"
/note="Rv0446c, (MTV037.10c), len: 256 aa. Possible
conserved transmembrane protein, similar at N-terminus to
U1740AF|U15183|MLU15183_40 from Mycobacterium leprae (117
aa), FASTA scores: opt: 175, E(): 2.5e-05, (62.5% identity
in 40 aa overlap); and at C-terminus to AL021529|SC10A5_3
from Streptomyces coelicolor (226 aa), FASTA scores: opt:
207, E(): 9.8e-07, (34.2% identity in 114 aa overlap).
Also similar to others hypothetical proteins e.g.
AAK04680.1|AE006291_14|AE006291 hypothetical protein from
Lactococcus lactis subsp. lactis (257 aa)."
/db_xref="EnsemblGenomes-Gn:Rv0446c"
/db_xref="EnsemblGenomes-Tr:CCP43177"
/db_xref="GOA:O53731"
/db_xref="InterPro:IPR001104"
/db_xref="InterPro:IPR010721"
/db_xref="UniProtKB/TrEMBL:O53731"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MVTSVSALAV AVVHSVAFAI GRRIGRYNVV DVVWGLGFVA VAVAAATLGH GDPVRRWLLL
61 ALVSTWGLRL SWHMYRKTAG QGEDPRYADL LRGATPVQAL RKVFGLQGLL TLFVSFPLQL
121 SAVTGPTPKP LLAVGGVGLA VWLVGITFEA VGDWQLWVFK SDPANRGVIM DRGLWAWTRH
181 PNYFGDACVW WGLWLITIND WAPLATVGSP LLMTYLLVDV SGARLTERYL KGRPGFAEYQ
241 RRTAYFVPRP PRSARR
//