LOCUS CCP43145.1 222 aa PRT BCT 27-FEB-2015
DEFINITION Mycobacterium tuberculosis H37Rv Thiamine-phosphate pyrophosphorylas
e ThiE (TMP pyrophosphorylase) (TMP-PPASE) (thiamine-phosphate
synthase) protein.
ACCESSION AL123456-423
PROTEIN_ID CCP43145.1
SOURCE Mycobacterium tuberculosis H37Rv
ORGANISM Mycobacterium tuberculosis H37Rv
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE 1
AUTHORS Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
Barrell B.G.
TITLE Deciphering the biology of Mycobacterium tuberculosis from the
complete genome sequence
JOURNAL Nature 393(6685), 537-544(1998).
PUBMED 9634230
REMARK Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE 2
AUTHORS Camus J.C., Pryor M.J., Medigue C., Cole S.T.
TITLE Re-annotation of the genome sequence of Mycobacterium tuberculosis
H37Rv
JOURNAL Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
PUBMED 12368430
REFERENCE 3
AUTHORS Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
TITLE TubercuList--10 years after
JOURNAL Tuberculosis (Edinb) 91(1), 1-7(2011).
PUBMED 20980199
REFERENCE 4 (bases 1 to 4411529)
AUTHORS Parkhill J.
JOURNAL Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
Mycobacterium tuberculosis sequencing and mapping teams, Sanger
Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
parkhill@sanger.ac.uk
REFERENCE 5 (bases 1 to 4411532)
AUTHORS Lew J.M.
JOURNAL Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
4, SWITZERLAND
COMMENT On or before Feb 1, 2013 this sequence version replaced
gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
gi:38490319, gi:41352785, gi:38490370, gi:41353971.
Note:
This annotation is from the TubercuList website, Release 26, Dec
2012 (URL: http://tuberculist.epfl.ch) (email:
tuberculist@epfl.ch).
FEATURES Qualifiers
source /organism="Mycobacterium tuberculosis H37Rv"
/strain="H37Rv"
/mol_type="genomic DNA"
/db_xref="taxon:83332"
protein /transl_table=11
/gene="thiE"
/locus_tag="Rv0414c"
/note="Rv0414c, (MTCY22G10.11c), len: 222 aa. thiE,
thiamin phosphate pyrophosphorylase, equivalent to
Q9ZBL5|AL035159|MLCB1450_17 probable thiamine-phosphate
pyrophosphorylase from Mycobacterium leprae (235 aa),
FASTA scores: opt: 1095, E(): 0, (78.0% identity in 223 aa
overlap). Also similar to others e.g.
T34974|5689976|CAB52013.1|AL109663 probable thiamin
phosphate pyrophosphorylase from Streptomyces coelicolor
(223 aa); THIE_ECOLI|P30137 thie protein from Escherichia
coli strain K12 (211 aa), FASTA scores: opt: 275, E():
7.8e-12, (37.8% identity in 196 aa overlap); etc. Belongs
to the TMP-PPASE family."
/db_xref="EnsemblGenomes-Gn:Rv0414c"
/db_xref="EnsemblGenomes-Tr:CCP43145"
/db_xref="GOA:P9WG75"
/db_xref="InterPro:IPR013785"
/db_xref="InterPro:IPR022998"
/db_xref="InterPro:IPR034291"
/db_xref="InterPro:IPR036206"
/db_xref="PDB:3O63"
/db_xref="UniProtKB/Swiss-Prot:P9WG75"
/experiment="EXISTENCE: identified in proteomics study"
BEGIN
1 MHESRLASAR LYLCTDARRE RGDLAQFAEA ALAGGVDIIQ LRDKGSPGEL RFGPLQARDE
61 LAACEILADA AHRYGALFAV NDRADIARAA GADVLHLGQR DLPVNVARQI LAPDTLIGRS
121 THDPDQVAAA AAGDADYFCV GPCWPTPTKP GRAAPGLGLV RVAAELGGDD KPWFAIGGIN
181 AQRLPAVLDA GARRIVVVRA ITSADDPRAA AEQLRSALTA AN
//