LOCUS       CCP42772.1               678 aa    PRT              BCT 27-FEB-2015
DEFINITION  Mycobacterium tuberculosis H37Rv Probable bifunctional
            penicillin-binding protein 1A/1B PonA1 (murein polymerase)
            (PBP1): penicillin-insensitive transglycosylase (peptidoglycan
            TGASE) + penicillin-sensitive transpeptidase (DD-transpeptidase)
            protein.
ACCESSION   AL123456-50
PROTEIN_ID  CCP42772.1
SOURCE      Mycobacterium tuberculosis H37Rv
  ORGANISM  Mycobacterium tuberculosis H37Rv
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.,
            Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III.,
            Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
            Connor R., Davies R., Devlin K., Feltwell T., Gentles S.,
            Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J.,
            Moule S., Murphy L., Oliver K., Osborne J., Quail M.A.,
            Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
            Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
            Barrell B.G.
  TITLE     Deciphering the biology of Mycobacterium tuberculosis from the
            complete genome sequence
  JOURNAL   Nature 393(6685), 537-544(1998).
   PUBMED   9634230
  REMARK    Erratum:[Nature 1998 Nov 12;396(6707):190]
REFERENCE   2
  AUTHORS   Camus J.C., Pryor M.J., Medigue C., Cole S.T.
  TITLE     Re-annotation of the genome sequence of Mycobacterium tuberculosis
            H37Rv
  JOURNAL   Microbiology (Reading, Engl.) 148(Pt 10), 2967-2973(2002).
   PUBMED   12368430
REFERENCE   3
  AUTHORS   Lew J.M., Kapopoulou A., Jones L.M., Cole S.T.
  TITLE     TubercuList--10 years after
  JOURNAL   Tuberculosis (Edinb) 91(1), 1-7(2011).
   PUBMED   20980199
REFERENCE   4  (bases 1 to 4411529)
  AUTHORS   Parkhill J.
  JOURNAL   Submitted (11-JUN-1998) to the INSDC. Submitted on behalf of the
            Mycobacterium tuberculosis sequencing and mapping teams, Sanger
            Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA
            Unite de Genetique Moleculaire Bacterienne, Institut Pasteur, 28
            rue du Docteur Roux, 75724 Paris Cedex 15, France E-mail:
            parkhill@sanger.ac.uk
REFERENCE   5  (bases 1 to 4411532)
  AUTHORS   Lew J.M.
  JOURNAL   Submitted (18-DEC-2012) to the INSDC. Lew J., Ecole Polytechnique
            Federale de Lausanne, CH-1015, Lausanne, Switzerland, and the Swiss
            Institute of Bioinformatics, CMU - Rue Michel-Servet 1, 1211 Geneva
            4, SWITZERLAND
COMMENT     On or before Feb 1, 2013 this sequence version replaced
            gi:41352722, gi:38490165, gi:38490207, gi:41353619, gi:38490250,
            gi:38684030, gi:38490288, gi:41353667, gi:41353422, gi:41352756,
            gi:38490319, gi:41352785, gi:38490370, gi:41353971.
            Note:
            This annotation is from the TubercuList website, Release 26, Dec
            2012 (URL: http://tuberculist.epfl.ch) (email:
            tuberculist@epfl.ch).
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37Rv"
                     /strain="H37Rv"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:83332"
     protein         /transl_table=11
                     /gene="ponA1"
                     /locus_tag="Rv0050"
                     /note="Rv0050, (MTCY21D4.13), len: 678 aa. Probable
                     ponA1,penicillin-binding protein (class A), bienzymatic
                     protein with transglycosylase and transpeptidase
                     activities (see Graham & Clark-Curtiss 1999), highly
                     similar to many (see Billman-Jacobe et al., 1999). Belongs
                     to the transglycosylase family in the N-terminal section,
                     and to the transpeptidase family in the C-terminal
                     section."
                     /db_xref="EnsemblGenomes-Gn:Rv0050"
                     /db_xref="EnsemblGenomes-Tr:CCP42772"
                     /db_xref="GOA:P71707"
                     /db_xref="InterPro:IPR001264"
                     /db_xref="InterPro:IPR001460"
                     /db_xref="InterPro:IPR012338"
                     /db_xref="InterPro:IPR023346"
                     /db_xref="InterPro:IPR036950"
                     /db_xref="PDB:5CRF"
                     /db_xref="PDB:5CXW"
                     /db_xref="UniProtKB/Swiss-Prot:P71707"
                     /experiment="EXISTENCE: identified in proteomics study"
BEGIN
        1 MVILLPMVTF TMAYLIVDVP KPGDIRTNQV STILASDGSE IAKIVPPEGN RVDVNLSQVP
       61 MHVRQAVIAA EDRNFYSNPG FSFTGFARAV KNNLFGGDLQ GGSTITQQYV KNALVGSAQH
      121 GWSGLMRKAK ELVIATKMSG EWSKDDVLQA YLNIIYFGRG AYGISAASKA YFDKPVEQLT
      181 VAEGALLAAL IRRPSTLDPA VDPEGAHARW NWVLDGMVET KALSPNDRAA QVFPETVPPD
      241 LARAENQTKG PNGLIERQVT RELLELFNID EQTLNTQGLV VTTTIDPQAQ RAAEKAVAKY
      301 LDGQDPDMRA AVVSIDPHNG AVRAYYGGDN ANGFDFAQAG LQTGSSFKVF ALVAALEQGI
      361 GLGYQVDSSP LTVDGIKITN VEGEGCGTCN IAEALKMSLN TSYYRLMLKL NGGPQAVADA
      421 AHQAGIASSF PGVAHTLSED GKGGPPNNGI VLGQYQTRVI DMASAYATLA ASGIYHPPHF
      481 VQKVVSANGQ VLFDASTADN TGDQRIPKAV ADNVTAAMEP IAGYSRGHNL AGGRDSAAKT
      541 GTTQFGDTTA NKDAWMVGYT PSLSTAVWVG TVKGDEPLVT ASGAAIYGSG LPSDIWKATM
      601 DGALKGTSNE TFPKPTEVGG YAGVPPPPPP PEVPPSETVI QPTVEIAPGI TIPIGPPTTI
      661 TLAPPPPAPP AATPTPPP
//