LOCUS CCO25891.1 1088 aa PRT CON 06-FEB-2024
DEFINITION Caenorhabditis elegans Ras GTPase-activating protein gap-2 protein.
ACCESSION BX284606-2218
PROTEIN_ID CCO25891.1
SOURCE Caenorhabditis elegans
ORGANISM Caenorhabditis elegans
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
Caenorhabditis.
REFERENCE 1 (bases 1 to 17718942)
AUTHORS WormBase.
CONSRTM WormBase Consortium
JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European
Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email:
help@wormbase.org
REFERENCE 2 (bases 1 to 17718942)
AUTHORS Sulson J.E., Waterston R.
JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project:
Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome
Institute at Washington University, St. Louis, MO 63110, USA.
REFERENCE 3 (bases 1 to 17718942)
AUTHORS Sulson J.E., Waterston R.
CONSRTM Caenorhabditis elegans Sequencing Consortium
TITLE Genome sequence of the nematode C. elegans: a platform for
investigating biology
JOURNAL Science 282(5396), 2012-2018(1998).
COMMENT Annotated features correspond to WormBase release WS292.
Protein-coding gene structures below are the result of integration
and manual review of the following types of data: ab initio
predictions by Genefinder (P. Green and L. Hillier, pers. comm.);
alignments to published proteins and cDNAs; genome sequence
conservation with other nematodes (e.g. to C. briggsae using WABA:
Genome Res. 2000. 10:1115-1125); sequence features (such as
trans-splice and polyA sites).
Sources of data: large-scale EST projects of Yuji Kohara
(http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome
cloning project (http://worfdb.dfci.harvard.edu); RST large-scale
sequencing project (Genome Res. 2009. 19:2334-2342); IST library
(Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010
Unpublished); UTRome EST data submission (UTRome v1 Mangone M.
Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep
sequencing data (454 read clusters - Makedonka Mitreva,
unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66);
Numerous data sets from the modENCODE project (Science. 2010.
330:1775-87); Individual C. elegans Nucleotide Database
submissions; Personal communications with C. elegans researchers;
Non-Coding gene structures below are derived using the following
methods and data: ab initio prediction of tRNAs by tRNAscan-SE
(Nucl. Acids. Res., 25, 955-964); integration and appraisal of
miRNAs from miRBase (http://www.mirbase.org); integration and
appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell.
2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87);
manual curation of novel published ncRNAs from the literature.
FEATURES Qualifiers
source /organism="Caenorhabditis elegans"
/chromosome="X"
/strain="Bristol N2"
/mol_type="genomic DNA"
/db_xref="taxon:6239"
protein /transl_table=1
/gene="gap-2"
/locus_tag="CELE_ZK899.8"
/standard_name="ZK899.8h"
/note="Confirmed by transcript evidence"
/db_xref="EnsemblGenomes-Gn:WBGene00001516"
/db_xref="EnsemblGenomes-Tr:ZK899.8h"
/db_xref="GOA:Q8MLZ5"
/db_xref="InterPro:IPR000008"
/db_xref="InterPro:IPR001849"
/db_xref="InterPro:IPR001936"
/db_xref="InterPro:IPR008936"
/db_xref="InterPro:IPR023152"
/db_xref="InterPro:IPR035892"
/db_xref="InterPro:IPR039360"
/db_xref="UniProtKB/Swiss-Prot:Q8MLZ5"
/db_xref="WormBase:WBGene00001516"
intron_pos 36:1 (1/16)
intron_pos 110:0 (2/16)
intron_pos 130:0 (3/16)
intron_pos 160:2 (4/16)
intron_pos 218:1 (5/16)
intron_pos 258:2 (6/16)
intron_pos 325:2 (7/16)
intron_pos 370:2 (8/16)
intron_pos 446:0 (9/16)
intron_pos 560:2 (10/16)
intron_pos 673:2 (11/16)
intron_pos 760:2 (12/16)
intron_pos 885:2 (13/16)
intron_pos 950:0 (14/16)
intron_pos 1006:2 (15/16)
intron_pos 1059:0 (16/16)
BEGIN
1 MRRYGISPWY SQSTYSLNII PEEYVPPVDY DIDFRDAIHD ETNSGGAQVG GESLDRRGWS
61 GASTGNRTTL TASVHNNLMN GRMSSSSHNL STRLSGSTQN LNQPTNAYGF PIVPPANNPS
121 DSSASGRIAN LLSRPFRSNP LKRTKSVSKM EKSLAEANQH SLHRVDASNT PSRDSSLYAQ
181 PPARRHLSQP AREGSLRACR SHESLLSSAH STHMIELNED NRLHPVHPSI FEVPNCFRLA
241 STYYSCRTPL ERAKWMENLR KTMNPRRDQQ RRTENSMLIW ILEAKGLPAK RKYYCEMTLD
301 KTLYAKTSSK ARTDNVFWGE NFEFMMLPKI DEVCVSLFRE SDSKKKKDTL IGYVTIGIDQ
361 LSSRSPVERW YTVNTSHSDS GTSRIASALG GKSSSQESPS LRIKARWQSV HILPLRAYDN
421 LLETLCYNYL PLCEQLEPVL NVRDKEDLAT SLVRVMYKHN LAKEFLCDLI MKEVEKLDND
481 HLMFRGNTLA TKAMESFMKL VADDYLDSTL SDFIKTVLQC EDSCEVDPQK LGNVSNSSLE
541 KNRALLMRYV EVAWTKILNN VHQLPKNLRD VFSALRCRLE AQNREALADT LISSSIFLRF
601 LCPAILSPSL FNLVSEYPSP TNARNLTLIA KTLQNLANFS KFGGKEPHME FMNEFVDREW
661 HRMKDFLLRI SSESKSGPEK NADAIVDAGK ELSLIATYLE EAWTPLLQEK NGNKHPLSNV
721 KSVLSELAEC KRRSDNGVFH SPMVQQPSSD YENSPQQHVV PRHENVPAYR STPPTGQATV
781 LGRSTNRPAT HLLTSDDYVL SSAFQTPSLR PGGTRLSDET GTSSSRTSDK TTSSAEIRDD
841 TDSDFELRED RGRGGRNRKR LPRTDASPSS SQQASSGYLS NNPSRSSYSN SSSSSPVERM
901 AALSIANPVF GPGPSSGYAI PAEPKEIVYQ KRASPPPYDP DVHNYHYQPM QVYAVPPDCQ
961 VSPRTQATGG VNAQNRLSLP RTNPRASRNS TLLRPSVVNV PDDWDRTSDY WRDRGENNYR
1021 SQLESQVESQ AREIERLMRE NIELKSKMMS STKTVDSKRS DSGASEDSYD SLSSLDRPSR
1081 QSLVVVPN
//