LOCUS CCD83387.1 1383 aa PRT CON 06-FEB-2024
DEFINITION Caenorhabditis elegans NPC intracellular cholesterol transporter
1 homolog 1 protein.
ACCESSION BX284606-991
PROTEIN_ID CCD83387.1
SOURCE Caenorhabditis elegans
ORGANISM Caenorhabditis elegans
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
Caenorhabditis.
REFERENCE 1 (bases 1 to 17718942)
AUTHORS WormBase.
CONSRTM WormBase Consortium
JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European
Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email:
help@wormbase.org
REFERENCE 2 (bases 1 to 17718942)
AUTHORS Sulson J.E., Waterston R.
JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project:
Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome
Institute at Washington University, St. Louis, MO 63110, USA.
REFERENCE 3 (bases 1 to 17718942)
AUTHORS Sulson J.E., Waterston R.
CONSRTM Caenorhabditis elegans Sequencing Consortium
TITLE Genome sequence of the nematode C. elegans: a platform for
investigating biology
JOURNAL Science 282(5396), 2012-2018(1998).
COMMENT Annotated features correspond to WormBase release WS292.
Protein-coding gene structures below are the result of integration
and manual review of the following types of data: ab initio
predictions by Genefinder (P. Green and L. Hillier, pers. comm.);
alignments to published proteins and cDNAs; genome sequence
conservation with other nematodes (e.g. to C. briggsae using WABA:
Genome Res. 2000. 10:1115-1125); sequence features (such as
trans-splice and polyA sites).
Sources of data: large-scale EST projects of Yuji Kohara
(http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome
cloning project (http://worfdb.dfci.harvard.edu); RST large-scale
sequencing project (Genome Res. 2009. 19:2334-2342); IST library
(Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010
Unpublished); UTRome EST data submission (UTRome v1 Mangone M.
Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep
sequencing data (454 read clusters - Makedonka Mitreva,
unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66);
Numerous data sets from the modENCODE project (Science. 2010.
330:1775-87); Individual C. elegans Nucleotide Database
submissions; Personal communications with C. elegans researchers;
Non-Coding gene structures below are derived using the following
methods and data: ab initio prediction of tRNAs by tRNAscan-SE
(Nucl. Acids. Res., 25, 955-964); integration and appraisal of
miRNAs from miRBase (http://www.mirbase.org); integration and
appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell.
2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87);
manual curation of novel published ncRNAs from the literature.
FEATURES Qualifiers
source /organism="Caenorhabditis elegans"
/chromosome="X"
/strain="Bristol N2"
/mol_type="genomic DNA"
/db_xref="taxon:6239"
protein /transl_table=1
/gene="ncr-1"
/locus_tag="CELE_F02E8.6"
/standard_name="F02E8.6"
/note="Confirmed by transcript evidence"
/db_xref="EnsemblGenomes-Gn:WBGene00003561"
/db_xref="EnsemblGenomes-Tr:F02E8.6"
/db_xref="WormBase:WBGene00003561"
intron_pos 71:1 (1/16)
intron_pos 125:0 (2/16)
intron_pos 219:0 (3/16)
intron_pos 270:0 (4/16)
intron_pos 311:0 (5/16)
intron_pos 403:2 (6/16)
intron_pos 485:0 (7/16)
intron_pos 528:2 (8/16)
intron_pos 764:1 (9/16)
intron_pos 859:0 (10/16)
intron_pos 889:0 (11/16)
intron_pos 1049:2 (12/16)
intron_pos 1192:0 (13/16)
intron_pos 1255:0 (14/16)
intron_pos 1307:2 (15/16)
intron_pos 1350:1 (16/16)
BEGIN
1 MKQLLIFCLL FGSIFHHGDA GCIMRGLCQK HTENAYGPCV TNDTNVEPTA FDKTHPAYEK
61 MVEFCPHLLT GDNKLCCTPS QAEGLTKQIA QARHILGRCP SCFDNFAKLW CEFTCSPNQQ
121 DFVSISEMKP IEKKEGFTPE YQPAEAYVNT VEYRLSTDFA EGMFSSCKDV TFGGQPALRV
181 MCTSTPCTLT NWLEFIGTQN LDLNIPIHTK FLLYDPIKTP PSDRSTYMNV NFTGCDKSAR
241 VGWPACSTSE CNKEEYANLI DLDDGKTSGQ TCNVHGIACL NIFVMLAFIG SLAVLLCVGF
301 VFTSYDEDYT NLRQTQSGEE SPKRNRIKRT GAWIHNFMEN NARDIGMMAG RNPKSHFFIG
361 CAVLIFCLPG MIYHKESTNV VDMWSSPRSR ARQEEMVFNA NFGRPQRYQQ IMLLSHRDFQ
421 SSGKLYGPVF HKDIFEELFD ILNAIKNIST QDSDGRTITL DDVCYRPMGP GYDCLIMSPT
481 NYFQGNKEHL DMKSNKEETV SEDDDAFDYF SSEATTDEWM NHMAACIDQP MSQKTKSGLS
541 CMGTYGGPSA PNMVFGKNST NHQAANSIMM TILVTQRTEP EIQKAELWEK EFLKFCKEYR
601 EKSPKVIFSF MAERSITDEI ENDAKDEIVT VVIALAFLIG YVTFSLGRYF VCENQLWSIL
661 VHSRICLGML SVIINLLSSF CSWGIFSMFG IHPVKNALVV QFFVVTLLGV CRTFMVVKYY
721 AQQRVSMPYM SPDQCPEIVG MVMAGTMPAM FSSSLGCAFS FFIGGFTDLP AIRTFCLYAG
781 LAVLIDVVLH CTIFLALFVW DTQRELNGKP EFFFPYQIKD LLGAYLIGRQ RATDTFMTQF
841 FHFQVAPFLM HRMTRIITGI IFIASFITTV ILSSKISVGF DQSMAFTEKS YISTHFRYLD
901 KFFDVGPPVF FTVDGELDWH RPDVQNKFCT FPGCSDTSFG NIMNYAVGHT EQTYLSGEMY
961 NWIDNYLEWI SRKSPCCKVY VHDPNTFCST NRNKSALDDK ACRTCMDFDY VANSYPKSSI
1021 MYHRPSIEVF YRHLRHFLED TPNSECVFGG RASFKDAISF TSRGRIQASQ FMTFHKKLSI
1081 SNSSDFIKAM DTARMVSRRL ERSIDDTAHV FAYSKIFPFY EQYSTIMPIL TTQLFITVVG
1141 VFGIICVTLG IDVKGAACAV ICQVSNYFHI VAFMYIFNIP VNALSATNLV MSSGILIEFS
1201 VNVLKGYACS LRQRAKDRAE STVGSIGPII LSGPVVTMAG STMFLSGAHL QIITVYFFKL
1261 FLITIVSSAV HALIILPILL AFGGSRGHGS SETSTNDNDE QHDACVLSPT AESHISNVEE
1321 GILNRPSLLD ASHILDPLLK AEGGIDKAID IITIDRSYPS TPSSLPCTSR MPRAHIEPDL
1381 RSL
//