LOCUS       CCD73727.1               842 aa    PRT              CON 06-FEB-2024
DEFINITION  Caenorhabditis elegans DNA topoisomerase-like protein
            cin-4 protein.
ACCESSION   BX284602-2517
PROTEIN_ID  CCD73727.1
SOURCE      Caenorhabditis elegans
  ORGANISM  Caenorhabditis elegans
            Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
            Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
            Caenorhabditis.
REFERENCE   1  (bases 1 to 15279421)
  AUTHORS   WormBase.
  CONSRTM   WormBase Consortium
  JOURNAL   Submitted (04-FEB-2024) to the INSDC. WormBase Group, European
            Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email:
            help@wormbase.org
REFERENCE   2  (bases 1 to 15279421)
  AUTHORS   Sulson J.E., Waterston R.
  JOURNAL   Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project:
            Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome
            Institute at Washington University, St. Louis, MO 63110, USA.
REFERENCE   3  (bases 1 to 15279421)
  AUTHORS   Sulson J.E., Waterston R.
  CONSRTM   Caenorhabditis elegans Sequencing Consortium
  TITLE     Genome sequence of the nematode C. elegans: a platform for
            investigating biology
  JOURNAL   Science 282(5396), 2012-2018(1998).
COMMENT     Annotated features correspond to WormBase release WS292.
            Protein-coding gene structures below are the result of integration
            and manual review of the following types of data: ab initio
            predictions by Genefinder (P. Green and L. Hillier, pers. comm.);
            alignments to published proteins and cDNAs; genome sequence
            conservation with other nematodes (e.g. to C. briggsae using WABA:
            Genome Res. 2000. 10:1115-1125); sequence features (such as
            trans-splice and polyA sites).
            Sources of data: large-scale EST projects of Yuji Kohara
            (http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome
            cloning project (http://worfdb.dfci.harvard.edu); RST large-scale
            sequencing project (Genome Res. 2009. 19:2334-2342); IST library
            (Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010
            Unpublished); UTRome EST data submission (UTRome v1 Mangone M.
            Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep
            sequencing data (454 read clusters - Makedonka Mitreva,
            unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66);
            Numerous data sets from the modENCODE project (Science. 2010.
            330:1775-87); Individual C. elegans Nucleotide Database
            submissions; Personal communications with C. elegans researchers;
            Non-Coding gene structures below are derived using the following
            methods and data: ab initio prediction of tRNAs by tRNAscan-SE
            (Nucl. Acids. Res., 25, 955-964); integration and appraisal of
            miRNAs from miRBase (http://www.mirbase.org); integration and
            appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell.
            2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87);
            manual curation of novel published ncRNAs from the literature.
FEATURES             Qualifiers
     source          /organism="Caenorhabditis elegans"
                     /chromosome="II"
                     /strain="Bristol N2"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:6239"
     protein         /transl_table=1
                     /gene="cin-4"
                     /locus_tag="CELE_ZK1127.7"
                     /standard_name="ZK1127.7"
                     /note="Confirmed by transcript evidence"
                     /db_xref="EnsemblGenomes-Gn:WBGene00022854"
                     /db_xref="EnsemblGenomes-Tr:ZK1127.7"
                     /db_xref="GOA:G5ECQ8"
                     /db_xref="InterPro:IPR001241"
                     /db_xref="InterPro:IPR002205"
                     /db_xref="InterPro:IPR013757"
                     /db_xref="InterPro:IPR013758"
                     /db_xref="InterPro:IPR013759"
                     /db_xref="InterPro:IPR013760"
                     /db_xref="InterPro:IPR018522"
                     /db_xref="InterPro:IPR031660"
                     /db_xref="UniProtKB/Swiss-Prot:G5ECQ8"
                     /db_xref="WormBase:WBGene00022854"
     intron_pos      39:0 (1/2)
     intron_pos      822:2 (2/2)
BEGIN
        1 MSEEDRNVFT SIDKKGGGSK QMDDLNQKCP KRKTSKLKGI PKLEDANDAG TKNSQQCTLI
       61 LTEGDSAKTL AVSGLSVVGR DKYGVFPFRR KLLNVCDLNV NQIADSAEVN AIIKILGLQY
      121 TKKYETEDDF KTLRYGKLLI MANHDSDGSQ FKGLLLNFFH RFWPALFKRD FVEDFITPIA
      181 KATEGKEEVS FYSLPEYSEW RMNTDNWKSY TIKYYNGLGT LTSKEAKKCF SDMVRHRIRF
      241 KYNGADDDKA VNMAFSKKKI EARTDYLMKL MQDKNQRKQQ GLAEECLYNK ETRFVTLKDF
      301 FNYEIVCSWN LHSIPCLVDG LKPGQRKVLF ACFKRANKRE VKVAQLAGAV AEISAYHHGE
      361 QSLMGTIVNL AQDYVGSHNI NLLLPIGQFG TRLQGGKDSA SARSIFAQLS QVTRTLFPAH
      421 DDNVLRFLYE ENQRIEPEWY CPIIPMVLVN GAQGTGTGWS TNIPNYNPRE LVKNIKRLIA
      481 GEPQKALAPW YKNFRGKIIQ IDPSRFACYG EVSVLDDNTI EITELPIKQW TQDYKEKVLE
      541 GLMESSDKKS PVIVDYKEYH TDTTVKFVVK LSPGKLRELE RGQDLHQVFK LQAVINTTCM
      601 VLFDAAGWLR TYTSPEAITQ EFYDSRQEKY VQRKEYLLGV LQAQSKRLTN QARFILATIN
      661 NKIVLENKKK TAIVDVLIKM KFDADPVKKW KEDQKLKELR ESGEIELDED DLAAVAVEEG
      721 EDISSAAKAV ETKLSDYDYL VGLALIKLSE EEKNKLIKES EEKMAEVRVL EKKTWQDLWI
      781 TDLDNFMSEL TSRRLARKLS LRRTATRWYA MICQRRVTWS SMKESISIRT MTVWSVRMSS
      841 RS
//