LOCUS CCD73727.1 842 aa PRT CON 06-FEB-2024 DEFINITION Caenorhabditis elegans DNA topoisomerase-like protein cin-4 protein. ACCESSION BX284602-2517 PROTEIN_ID CCD73727.1 SOURCE Caenorhabditis elegans ORGANISM Caenorhabditis elegans Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. REFERENCE 1 (bases 1 to 15279421) AUTHORS WormBase. CONSRTM WormBase Consortium JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email: help@wormbase.org REFERENCE 2 (bases 1 to 15279421) AUTHORS Sulson J.E., Waterston R. JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project: Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome Institute at Washington University, St. Louis, MO 63110, USA. REFERENCE 3 (bases 1 to 15279421) AUTHORS Sulson J.E., Waterston R. CONSRTM Caenorhabditis elegans Sequencing Consortium TITLE Genome sequence of the nematode C. elegans: a platform for investigating biology JOURNAL Science 282(5396), 2012-2018(1998). COMMENT Annotated features correspond to WormBase release WS292. Protein-coding gene structures below are the result of integration and manual review of the following types of data: ab initio predictions by Genefinder (P. Green and L. Hillier, pers. comm.); alignments to published proteins and cDNAs; genome sequence conservation with other nematodes (e.g. to C. briggsae using WABA: Genome Res. 2000. 10:1115-1125); sequence features (such as trans-splice and polyA sites). Sources of data: large-scale EST projects of Yuji Kohara (http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome cloning project (http://worfdb.dfci.harvard.edu); RST large-scale sequencing project (Genome Res. 2009. 19:2334-2342); IST library (Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010 Unpublished); UTRome EST data submission (UTRome v1 Mangone M. Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep sequencing data (454 read clusters - Makedonka Mitreva, unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66); Numerous data sets from the modENCODE project (Science. 2010. 330:1775-87); Individual C. elegans Nucleotide Database submissions; Personal communications with C. elegans researchers; Non-Coding gene structures below are derived using the following methods and data: ab initio prediction of tRNAs by tRNAscan-SE (Nucl. Acids. Res., 25, 955-964); integration and appraisal of miRNAs from miRBase (http://www.mirbase.org); integration and appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell. 2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87); manual curation of novel published ncRNAs from the literature. FEATURES Qualifiers source /organism="Caenorhabditis elegans" /chromosome="II" /strain="Bristol N2" /mol_type="genomic DNA" /db_xref="taxon:6239" protein /transl_table=1 /gene="cin-4" /locus_tag="CELE_ZK1127.7" /standard_name="ZK1127.7" /note="Confirmed by transcript evidence" /db_xref="EnsemblGenomes-Gn:WBGene00022854" /db_xref="EnsemblGenomes-Tr:ZK1127.7" /db_xref="GOA:G5ECQ8" /db_xref="InterPro:IPR001241" /db_xref="InterPro:IPR002205" /db_xref="InterPro:IPR013757" /db_xref="InterPro:IPR013758" /db_xref="InterPro:IPR013759" /db_xref="InterPro:IPR013760" /db_xref="InterPro:IPR018522" /db_xref="InterPro:IPR031660" /db_xref="UniProtKB/Swiss-Prot:G5ECQ8" /db_xref="WormBase:WBGene00022854" intron_pos 39:0 (1/2) intron_pos 822:2 (2/2) BEGIN 1 MSEEDRNVFT SIDKKGGGSK QMDDLNQKCP KRKTSKLKGI PKLEDANDAG TKNSQQCTLI 61 LTEGDSAKTL AVSGLSVVGR DKYGVFPFRR KLLNVCDLNV NQIADSAEVN AIIKILGLQY 121 TKKYETEDDF KTLRYGKLLI MANHDSDGSQ FKGLLLNFFH RFWPALFKRD FVEDFITPIA 181 KATEGKEEVS FYSLPEYSEW RMNTDNWKSY TIKYYNGLGT LTSKEAKKCF SDMVRHRIRF 241 KYNGADDDKA VNMAFSKKKI EARTDYLMKL MQDKNQRKQQ GLAEECLYNK ETRFVTLKDF 301 FNYEIVCSWN LHSIPCLVDG LKPGQRKVLF ACFKRANKRE VKVAQLAGAV AEISAYHHGE 361 QSLMGTIVNL AQDYVGSHNI NLLLPIGQFG TRLQGGKDSA SARSIFAQLS QVTRTLFPAH 421 DDNVLRFLYE ENQRIEPEWY CPIIPMVLVN GAQGTGTGWS TNIPNYNPRE LVKNIKRLIA 481 GEPQKALAPW YKNFRGKIIQ IDPSRFACYG EVSVLDDNTI EITELPIKQW TQDYKEKVLE 541 GLMESSDKKS PVIVDYKEYH TDTTVKFVVK LSPGKLRELE RGQDLHQVFK LQAVINTTCM 601 VLFDAAGWLR TYTSPEAITQ EFYDSRQEKY VQRKEYLLGV LQAQSKRLTN QARFILATIN 661 NKIVLENKKK TAIVDVLIKM KFDADPVKKW KEDQKLKELR ESGEIELDED DLAAVAVEEG 721 EDISSAAKAV ETKLSDYDYL VGLALIKLSE EEKNKLIKES EEKMAEVRVL EKKTWQDLWI 781 TDLDNFMSEL TSRRLARKLS LRRTATRWYA MICQRRVTWS SMKESISIRT MTVWSVRMSS 841 RS //