LOCUS CCD70615.1 934 aa PRT CON 06-FEB-2024 DEFINITION Caenorhabditis elegans Rab GTPase-activating protein tbc- 11 protein. ACCESSION BX284606-201 PROTEIN_ID CCD70615.1 SOURCE Caenorhabditis elegans ORGANISM Caenorhabditis elegans Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. REFERENCE 1 (bases 1 to 17718942) AUTHORS WormBase. CONSRTM WormBase Consortium JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email: help@wormbase.org REFERENCE 2 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project: Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome Institute at Washington University, St. Louis, MO 63110, USA. REFERENCE 3 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. CONSRTM Caenorhabditis elegans Sequencing Consortium TITLE Genome sequence of the nematode C. elegans: a platform for investigating biology JOURNAL Science 282(5396), 2012-2018(1998). COMMENT Annotated features correspond to WormBase release WS292. Protein-coding gene structures below are the result of integration and manual review of the following types of data: ab initio predictions by Genefinder (P. Green and L. Hillier, pers. comm.); alignments to published proteins and cDNAs; genome sequence conservation with other nematodes (e.g. to C. briggsae using WABA: Genome Res. 2000. 10:1115-1125); sequence features (such as trans-splice and polyA sites). Sources of data: large-scale EST projects of Yuji Kohara (http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome cloning project (http://worfdb.dfci.harvard.edu); RST large-scale sequencing project (Genome Res. 2009. 19:2334-2342); IST library (Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010 Unpublished); UTRome EST data submission (UTRome v1 Mangone M. Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep sequencing data (454 read clusters - Makedonka Mitreva, unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66); Numerous data sets from the modENCODE project (Science. 2010. 330:1775-87); Individual C. elegans Nucleotide Database submissions; Personal communications with C. elegans researchers; Non-Coding gene structures below are derived using the following methods and data: ab initio prediction of tRNAs by tRNAscan-SE (Nucl. Acids. Res., 25, 955-964); integration and appraisal of miRNAs from miRBase (http://www.mirbase.org); integration and appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell. 2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87); manual curation of novel published ncRNAs from the literature. FEATURES Qualifiers source /organism="Caenorhabditis elegans" /chromosome="X" /strain="Bristol N2" /mol_type="genomic DNA" /db_xref="taxon:6239" protein /transl_table=1 /gene="tbc-11" /locus_tag="CELE_F35H12.2" /standard_name="F35H12.2b" /note="Partially confirmed by transcript evidence" /db_xref="EnsemblGenomes-Gn:WBGene00018075" /db_xref="EnsemblGenomes-Tr:F35H12.2b" /db_xref="GOA:H2KZZ6" /db_xref="InterPro:IPR000195" /db_xref="InterPro:IPR006020" /db_xref="InterPro:IPR011993" /db_xref="InterPro:IPR022164" /db_xref="InterPro:IPR033185" /db_xref="InterPro:IPR035969" /db_xref="UniProtKB/TrEMBL:H2KZZ6" /db_xref="WormBase:WBGene00018075" intron_pos 16:0 (1/18) intron_pos 39:0 (2/18) intron_pos 64:2 (3/18) intron_pos 107:2 (4/18) intron_pos 130:0 (5/18) intron_pos 202:0 (6/18) intron_pos 239:1 (7/18) intron_pos 268:1 (8/18) intron_pos 323:0 (9/18) intron_pos 374:1 (10/18) intron_pos 442:0 (11/18) intron_pos 564:0 (12/18) intron_pos 612:0 (13/18) intron_pos 641:2 (14/18) intron_pos 700:0 (15/18) intron_pos 824:0 (16/18) intron_pos 869:2 (17/18) intron_pos 906:2 (18/18) BEGIN 1 MEDFKDFTEV TQFTNVQYLG CSQLVNNDND NEMKALMKVL DEQKGAQTIN VTLVVPHNIS 61 GTVKLIDAQG KVLSSFSLVN IRFCIRGESS TSQNNCFGIS FTHKISVGEH NSSDILHQCH 121 VFRTSKAETA AKALYSFSYA FSNKNVSSES NRLEFQFESI LEVKENDGTV EKPSWKLCPQ 181 HNGVFKVRRD REKKIVVQLR QIDGFLLNIK KCFGMLLAAG RNLRHSDLQL LEMDRNATGT 241 DSAVFVIEAN WDPRVHMFEV LNTETPRDTR VFMTVAIDVI VSEISEPIRF SMEAMSRVFH 301 EHERFYKTPQ TVVSEEFTLV LEKSCDQSDP NDRKLTFISL ESDSDRKRSK QNLGKSPSRM 361 PTQLLHPTGD DESDCDEPLL SGSGKVSQEC KEEHLEMWDQ LIENWDQQSD RPQKISELVL 421 DGIPDKLRGR VWQLLSNVRI LAIDQPDLVE KYHIFLSQPC PSEQVIMRDI HRTFPAHDYF 481 KESQGKGQQS LYKISKVYSL YDEEVSYCQG LSFLAASLLL HMPEEQAFCT LVKIMFNYGL 541 RDLFKLGFDN LHLRFFQLTA LLKDYIPDLS HHLEHIGIET HMYASQWFLT LFTAKFPLQM 601 VFFILDLFLS QGMNTIFHIS LALLDDAKTD LLQLDFEGTL KYFRVSLPRK YRTEASTKCL 661 IHKAVKFRLN HSKLEVYENE YKRIKELERE NEDPVLRMEK EIGRHQANTL RLERENDDLA 721 HELVTSKIEL RRKLDVAEDQ IETSANAIER LTRQNMDILE ENKNLMREYE QIKEMYRRDV 781 LRLEENGSRA EKLLAEYKKL FSERSKRAEN EREHFEVQKK AIIARISDCD KCWPAVCEWE 841 KNRSPVHSAS TPTGPDLLTK LEEREDHIKN LEIDLAQTKL SLVEAECRNQ DLTHQLMAQS 901 ESDGKKWFKK TITQLKEVGS SLKHHERSNS SVTP //