LOCUS CCD69450.1 1534 aa PRT CON 06-FEB-2024
DEFINITION Caenorhabditis elegans Multidrug resistance-associated
protein 1 protein.
ACCESSION BX284606-115
PROTEIN_ID CCD69450.1
SOURCE Caenorhabditis elegans
ORGANISM Caenorhabditis elegans
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
Caenorhabditis.
REFERENCE 1 (bases 1 to 17718942)
AUTHORS WormBase.
CONSRTM WormBase Consortium
JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European
Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email:
help@wormbase.org
REFERENCE 2 (bases 1 to 17718942)
AUTHORS Sulson J.E., Waterston R.
JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project:
Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome
Institute at Washington University, St. Louis, MO 63110, USA.
REFERENCE 3 (bases 1 to 17718942)
AUTHORS Sulson J.E., Waterston R.
CONSRTM Caenorhabditis elegans Sequencing Consortium
TITLE Genome sequence of the nematode C. elegans: a platform for
investigating biology
JOURNAL Science 282(5396), 2012-2018(1998).
COMMENT Annotated features correspond to WormBase release WS292.
Protein-coding gene structures below are the result of integration
and manual review of the following types of data: ab initio
predictions by Genefinder (P. Green and L. Hillier, pers. comm.);
alignments to published proteins and cDNAs; genome sequence
conservation with other nematodes (e.g. to C. briggsae using WABA:
Genome Res. 2000. 10:1115-1125); sequence features (such as
trans-splice and polyA sites).
Sources of data: large-scale EST projects of Yuji Kohara
(http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome
cloning project (http://worfdb.dfci.harvard.edu); RST large-scale
sequencing project (Genome Res. 2009. 19:2334-2342); IST library
(Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010
Unpublished); UTRome EST data submission (UTRome v1 Mangone M.
Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep
sequencing data (454 read clusters - Makedonka Mitreva,
unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66);
Numerous data sets from the modENCODE project (Science. 2010.
330:1775-87); Individual C. elegans Nucleotide Database
submissions; Personal communications with C. elegans researchers;
Non-Coding gene structures below are derived using the following
methods and data: ab initio prediction of tRNAs by tRNAscan-SE
(Nucl. Acids. Res., 25, 955-964); integration and appraisal of
miRNAs from miRBase (http://www.mirbase.org); integration and
appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell.
2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87);
manual curation of novel published ncRNAs from the literature.
FEATURES Qualifiers
source /organism="Caenorhabditis elegans"
/chromosome="X"
/strain="Bristol N2"
/mol_type="genomic DNA"
/db_xref="taxon:6239"
protein /transl_table=1
/gene="mrp-1"
/locus_tag="CELE_F57C12.5"
/standard_name="F57C12.5b"
/note="Confirmed by transcript evidence"
/db_xref="EnsemblGenomes-Gn:WBGene00003407"
/db_xref="EnsemblGenomes-Tr:F57C12.5b"
/db_xref="GOA:Q95QE2"
/db_xref="InterPro:IPR003439"
/db_xref="InterPro:IPR003593"
/db_xref="InterPro:IPR005292"
/db_xref="InterPro:IPR011527"
/db_xref="InterPro:IPR017871"
/db_xref="InterPro:IPR027417"
/db_xref="InterPro:IPR036640"
/db_xref="UniProtKB/TrEMBL:Q95QE2"
/db_xref="WormBase:WBGene00003407"
intron_pos 16:0 (1/19)
intron_pos 77:0 (2/19)
intron_pos 118:1 (3/19)
intron_pos 204:0 (4/19)
intron_pos 424:0 (5/19)
intron_pos 533:0 (6/19)
intron_pos 611:1 (7/19)
intron_pos 736:0 (8/19)
intron_pos 783:1 (9/19)
intron_pos 859:1 (10/19)
intron_pos 1029:1 (11/19)
intron_pos 1081:0 (12/19)
intron_pos 1133:0 (13/19)
intron_pos 1159:0 (14/19)
intron_pos 1199:2 (15/19)
intron_pos 1244:0 (16/19)
intron_pos 1397:1 (17/19)
intron_pos 1433:2 (18/19)
intron_pos 1493:0 (19/19)
BEGIN
1 MFPLVRELVC GSDYELLETG WRNNSNIPQV TNCGQHTDFS TIPTLFLVIF SPILFYELYK
61 SRNSYLRSFS AISLRIIFCC LLVVDLTATV IYDFYLLFTK SPLYNAIHFY GDLVQYAGFC
121 LALVLTIACR NRGIITSGVI TLYWLLVVVC GVPELRYYIT GRLYKEYEIH SCRAALYVFA
181 YVCSALELFL SCFADTPSNG YIGKNSCPEY TASFLNQLTF QWFSGLAYLG NKKSLEKEDL
241 WDLNERDKAE NIIPSFIENL IPEVEGYRRK IKKNPEAAIP KNHPSILIPI FKTYKFTLLA
301 GGCYKLMFDL LQFVAPELLR QLISFIEDKN QPMWIGVSIA LLMFLSSLLQ SMILHQYFHE
361 MFRLGMNIRS VLTSAVYTKT LNLSNEARKG KTTGAIVNLM SVDIQRIQDM TTFIMLFWSA
421 PLQILLSLYF LWKLLGVSVL AGFVILILLI PFNSFISVKM RNCQMEQMKF KDERIKMMSE
481 ILNGMKVLKL YSWEKSMEKM VLEVREKEIR VLKKLSYLNA ATTLSWACAP FLVAVLTFGL
541 YVLWDPENNV LTPQITFVAL ALFNILRFPL AVFAMVFSQA VQCSASNTRL KEFFAAEEMS
601 PQTSIAYGGT DSAIKMDGGS FAWGSKEEDR KLHDITFNIK RGQLVAIVGR VGSGKSSLLH
661 ALLGEMNKLS GSVQVNGSVA YVPQLAWIQN LSLRNNILFN RPYDAKLYQN VIENCALVQD
721 LESLPAEDRT EIGEKGINLS GGQKQRVSLA RAVYQNAEIV LLDDPLSAVD SHVGKHIFEN
781 VISTATGCLG TKTRVLLTHG LTYLKHCDQV IVLKDETISE MGTYQELMNS NGAFSEFLEE
841 FLLEESKHKG RSVSFGEDSK EVNELLRDLD QVSPAIRQRI QSQMSQEIEK TDDKNAEIIR
901 NGLHKDEQTA HSSIGKSEEK ESLLGAISPK EKTPEPPKQT KTQLIEKEAV ETGKVKFEVY
961 MSYFRAIGIK IALVFFLVYV ASSMLGVFSN LYLARWSDDA KEIALSGNGS SSETQIRLGI
1021 YAVLGMGQAT SVCAASIIMA LGMVCASRLL HATLLENIMR SPMAFFDVTP LGRILNRFGK
1081 DIDVIDYRLP SCIMTFVGAI VQAVTIFAVP IYATPLSSFP ITIVLIGYYF LLRFYVSTSR
1141 QLKRLESASR SPIYSHFQES IQGASSIRAY GVVDKFIRES QHRVDENLAT YYPSIVANRW
1201 LAVRLEMVGN LIVLSSAGAA VYFRDSPGLS AGLVGLSVSY ALNITQTLNW AVRMTSELET
1261 NIVAVERINE YTITPTEGNN SQSLAPKSWP ENGEISIKNF SVRYRPGLDL VLHGVTAHIS
1321 PCEKIGIVGR TGAGKSSLTL ALFRIIEADG GCIEIDGTNI ADLLLEQLRS RLTIVPQDPV
1381 LFSGTMRMNL DPFFAFSDDQ IWEALRNAHL DSFVKSLQEG LHHHISEGGE NLSVGQRQLI
1441 CLARALLRKT KVLVLDEAAA AVDVETDSLL QKTIREQFKD CTVLTIAHRL NTVMDSDRLL
1501 VLDKGCVAEF DTPKKLLSNP DGIFYSMAKD ANVV
//