LOCUS CCD69448.1 1525 aa PRT CON 06-FEB-2024
DEFINITION Caenorhabditis elegans Multidrug resistance-associated
protein 1 protein.
ACCESSION BX284606-114
PROTEIN_ID CCD69448.1
SOURCE Caenorhabditis elegans
ORGANISM Caenorhabditis elegans
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
Caenorhabditis.
REFERENCE 1 (bases 1 to 17718942)
AUTHORS WormBase.
CONSRTM WormBase Consortium
JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European
Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email:
help@wormbase.org
REFERENCE 2 (bases 1 to 17718942)
AUTHORS Sulson J.E., Waterston R.
JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project:
Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome
Institute at Washington University, St. Louis, MO 63110, USA.
REFERENCE 3 (bases 1 to 17718942)
AUTHORS Sulson J.E., Waterston R.
CONSRTM Caenorhabditis elegans Sequencing Consortium
TITLE Genome sequence of the nematode C. elegans: a platform for
investigating biology
JOURNAL Science 282(5396), 2012-2018(1998).
COMMENT Annotated features correspond to WormBase release WS292.
Protein-coding gene structures below are the result of integration
and manual review of the following types of data: ab initio
predictions by Genefinder (P. Green and L. Hillier, pers. comm.);
alignments to published proteins and cDNAs; genome sequence
conservation with other nematodes (e.g. to C. briggsae using WABA:
Genome Res. 2000. 10:1115-1125); sequence features (such as
trans-splice and polyA sites).
Sources of data: large-scale EST projects of Yuji Kohara
(http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome
cloning project (http://worfdb.dfci.harvard.edu); RST large-scale
sequencing project (Genome Res. 2009. 19:2334-2342); IST library
(Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010
Unpublished); UTRome EST data submission (UTRome v1 Mangone M.
Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep
sequencing data (454 read clusters - Makedonka Mitreva,
unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66);
Numerous data sets from the modENCODE project (Science. 2010.
330:1775-87); Individual C. elegans Nucleotide Database
submissions; Personal communications with C. elegans researchers;
Non-Coding gene structures below are derived using the following
methods and data: ab initio prediction of tRNAs by tRNAscan-SE
(Nucl. Acids. Res., 25, 955-964); integration and appraisal of
miRNAs from miRBase (http://www.mirbase.org); integration and
appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell.
2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87);
manual curation of novel published ncRNAs from the literature.
FEATURES Qualifiers
source /organism="Caenorhabditis elegans"
/chromosome="X"
/strain="Bristol N2"
/mol_type="genomic DNA"
/db_xref="taxon:6239"
protein /transl_table=1
/gene="mrp-2"
/locus_tag="CELE_F57C12.4"
/standard_name="F57C12.4"
/note="Confirmed by transcript evidence"
/db_xref="EnsemblGenomes-Gn:WBGene00003408"
/db_xref="GOA:Q20943"
/db_xref="InterPro:IPR003439"
/db_xref="InterPro:IPR003593"
/db_xref="InterPro:IPR005292"
/db_xref="InterPro:IPR011527"
/db_xref="InterPro:IPR017871"
/db_xref="InterPro:IPR027417"
/db_xref="InterPro:IPR036640"
/db_xref="UniProtKB/TrEMBL:Q20943"
/db_xref="WormBase:WBGene00003408"
intron_pos 16:0 (1/17)
intron_pos 77:0 (2/17)
intron_pos 118:1 (3/17)
intron_pos 204:0 (4/17)
intron_pos 424:0 (5/17)
intron_pos 611:1 (6/17)
intron_pos 735:0 (7/17)
intron_pos 782:1 (8/17)
intron_pos 858:1 (9/17)
intron_pos 1020:1 (10/17)
intron_pos 1072:0 (11/17)
intron_pos 1124:0 (12/17)
intron_pos 1150:0 (13/17)
intron_pos 1235:0 (14/17)
intron_pos 1388:1 (15/17)
intron_pos 1424:2 (16/17)
intron_pos 1484:0 (17/17)
BEGIN
1 MFPLVRELVC GDKTELLEPG WKNRSSIPHV TKCGQHTDFS TIPTLFLVVF SFIVIYQLLH
61 TRTAQLRCFS PISFRIILGC LLVVDLIATV IYDLYLYVSQ SPNFEVVHFY GDLVQFGGIC
121 LALILTVACK NKGIITSGVI TLYWLLVVVC GIPEFRFYLS GFIYNEYALE GIRATLYIIA
181 FTFSALELFL CCFADVPSDM YKSESSCPEY TASFINRLTF QWFTGLAYLG NKKSLENEDL
241 WDLNEIDKAE NLIPSFMQNL KPRIDEYHQN IKKDPSAALP KNHPSFVIPI FKTYKYTLLA
301 GFFYKLCFDM LQFLAPQLLK QLIGFIEDKN QPVWIGCSIV GIMFFSSFLQ SMFLHQYYHS
361 MFRLGMHVRS VLTSAVYSKA LNLSNEARKG KTIGAIVNLM SVDIQKIQDM APTIMLFWSA
421 PLQIFLSIYF LWKFLGVAAL AGLVVLILAL PVNGLIAIQM RKCQTEQMKL KDERIKMMSE
481 ILNGMKVLKL YSWERSMENM VLKIRERELH ILKKLSYFMA AIVFSWICAP FLASVISFVV
541 YVYLDPENNV LTPEITFVAL SLFDILRMPL AMVAMVYGEA VQCSVSNTRL KEFFAAEEMS
601 PQTSISHGET DSAIEVENGL FSWSSDEDPT LREISFKIQK GQLVAIVGKV GSGKSSLLHA
661 LLGEMNKLSG SVQINGNIAY VPQQAWIQNM SLRNNILFNK PYDLENYEDV VKNCALKEDL
721 ANLPAGDRTE IGEKGINLSG GQKQRVSLAR AVYQNPDIIL LDDPLSAVDS HVGKHIFENV
781 ISSSTGCLAS KTRVLVTHGL TYLKHCDQLI VLKEGTISEL GTYQELLNNS GAFAEFLEEF
841 LIEESKTRGR VASIGDGSGE VDEILRDLGQ VKPGILKRLE SHLSQESDKE DTSARAIEYS
901 RDSSRRSVLL HSPRSQHEEN EALLGAISED VPAQENTQLI EKETVETGKV KFEVYIAYFQ
961 AISIPITLLF FFLYVGSSGL GILSNFYLAK LSDHAKSGNR TSSDAKMELG IYAVLGMGQS
1021 FVVLIASIIL TIGVLRASRI LHAGLLGNIM RSPMAFFDVT PIGRILNRIG KDIEAIDRTL
1081 PDVIRHMSMT IFNVVATLVV IMWATPWAGI AFAILSVIYF IVLRFYISTS RQLKRLESAS
1141 RSPIYSHFQE SIQGASSIRA FGVVDNFIKQ SQQRVDDHLI AYYPSIVANR WLAVRLEMVG
1201 NLIVLSAAGA AVYFRDSPGL SAGLVGLSVS YALNITQTLN WAVRMTSELE TNIVSVERIK
1261 EYTVTPTEGN NSRRLAAKSW PEKGEISIKN FSVRYRPGLD LVLHGISAHI APSEKVGIVG
1321 RTGAGKSSLT LALFRIIEAD GGSIEIDGIN IANLQLEQLR SCLTIVPQDP VLFSGTMKMN
1381 LDPFSAYSDS QVWEALENAH LKPFVKSLQD GLEHKISEGG ENLSVGQRQL ICLARALLRK
1441 TKVLVLDEAA AAVDVETDSL IQKTIREQFK ECTVLTIAHR LNTVMDSDRL LVLDKGRVAE
1501 FDSPKNLLAN PDGIFYSMAK DANVV
//