LOCUS CCD68926.2 732 aa PRT CON 06-FEB-2024 DEFINITION Caenorhabditis elegans NEPrilysin metallopeptidase family protein. ACCESSION BX284602-1174 PROTEIN_ID CCD68926.2 SOURCE Caenorhabditis elegans ORGANISM Caenorhabditis elegans Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. REFERENCE 1 (bases 1 to 15279421) AUTHORS WormBase. CONSRTM WormBase Consortium JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email: help@wormbase.org REFERENCE 2 (bases 1 to 15279421) AUTHORS Sulson J.E., Waterston R. JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project: Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome Institute at Washington University, St. Louis, MO 63110, USA. REFERENCE 3 (bases 1 to 15279421) AUTHORS Sulson J.E., Waterston R. CONSRTM Caenorhabditis elegans Sequencing Consortium TITLE Genome sequence of the nematode C. elegans: a platform for investigating biology JOURNAL Science 282(5396), 2012-2018(1998). COMMENT Annotated features correspond to WormBase release WS292. Protein-coding gene structures below are the result of integration and manual review of the following types of data: ab initio predictions by Genefinder (P. Green and L. Hillier, pers. comm.); alignments to published proteins and cDNAs; genome sequence conservation with other nematodes (e.g. to C. briggsae using WABA: Genome Res. 2000. 10:1115-1125); sequence features (such as trans-splice and polyA sites). Sources of data: large-scale EST projects of Yuji Kohara (http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome cloning project (http://worfdb.dfci.harvard.edu); RST large-scale sequencing project (Genome Res. 2009. 19:2334-2342); IST library (Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010 Unpublished); UTRome EST data submission (UTRome v1 Mangone M. Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep sequencing data (454 read clusters - Makedonka Mitreva, unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66); Numerous data sets from the modENCODE project (Science. 2010. 330:1775-87); Individual C. elegans Nucleotide Database submissions; Personal communications with C. elegans researchers; Non-Coding gene structures below are derived using the following methods and data: ab initio prediction of tRNAs by tRNAscan-SE (Nucl. Acids. Res., 25, 955-964); integration and appraisal of miRNAs from miRBase (http://www.mirbase.org); integration and appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell. 2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87); manual curation of novel published ncRNAs from the literature. FEATURES Qualifiers source /organism="Caenorhabditis elegans" /chromosome="II" /strain="Bristol N2" /mol_type="genomic DNA" /db_xref="taxon:6239" protein /transl_table=1 /gene="nep-13" /locus_tag="CELE_F39E9.4" /standard_name="F39E9.4" /note="Product from WormBase gene class nep" /note="Confirmed by transcript evidence" /db_xref="EnsemblGenomes-Gn:WBGene00018196" /db_xref="EnsemblGenomes-Tr:F39E9.4" /db_xref="GOA:Q400M1" /db_xref="InterPro:IPR000718" /db_xref="InterPro:IPR008753" /db_xref="InterPro:IPR018497" /db_xref="InterPro:IPR024079" /db_xref="InterPro:IPR042089" /db_xref="UniProtKB/TrEMBL:Q400M1" /db_xref="WormBase:WBGene00018196" intron_pos 2:2 (1/11) intron_pos 97:0 (2/11) intron_pos 142:1 (3/11) intron_pos 173:0 (4/11) intron_pos 211:1 (5/11) intron_pos 263:0 (6/11) intron_pos 297:0 (7/11) intron_pos 357:0 (8/11) intron_pos 486:0 (9/11) intron_pos 540:1 (10/11) intron_pos 677:0 (11/11) BEGIN 1 MNERDTENSR LLSSTQNLEV EEDGEEEGDD NEKVSKCCIY PLISIIICLV IIAICMGAVI 61 VFWRMDSAPQ AICKTDHNKT RDVCKTAECI TLSSTLLNWQ NTNIDPCEDF YEYSCGRYQE 121 HTLNDGIRAN EKDTIVMKLI RQFVLKNQST TSNSENALML LYEKCSLRYR MENRHQETEV 181 IQREVFENIR KIGSWPIADK NWNSSHFNLN NMLSNMASIH MLPFGLFETR VIELYPMNTT 241 AKQLVIRPTK LKFSIPQEEL VRAIRDLLSV NGITSIMKKV KEDVAESFAL DKEIGNIHID 301 PQPKPATLSE LQKAVPDIDF ERIIKSYLNP KTGNWSSLRT KIFSARFELF FGKNNNLSSI 361 IARTKPRILA NYLFLKYIEY AYFFFFDNTK VFSDDDFCTE VVTTSLPRAS LRVFVRNHFK 421 KENMAVASEI VEVVKTAYVE IINNSTWLHN STRESAIEKV VKMKKVIGYT EEYERTGALD 481 EMFETLQLSR SDSFFVLMTK VNRFKIEQLM DFVSSDSLLN PIEPLVMANA FYFPTKNLLN 541 VLVPFLDKPL FDFKYPRYVA MAGVGRVLAH EIGHAFDING RQTDEIGRTR DWWTREDTEE 601 YDRRSECFAE QFTNFKDPSF KGKQNGTEVL AEIIADALGM EASWIAFKKI NLTEEQGLIQ 661 FEDHDFGKLY FQVAALDFCA PSRIEERYSD QLSHPTNKFR INGAFSNSRA FADTYKCPVG 721 SKMNPVQRCD MF //