LOCUS CCD68838.1 768 aa PRT CON 06-FEB-2024 DEFINITION Caenorhabditis elegans Degenerin mec-4 protein. ACCESSION BX284606-3929 PROTEIN_ID CCD68838.1 SOURCE Caenorhabditis elegans ORGANISM Caenorhabditis elegans Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. REFERENCE 1 (bases 1 to 17718942) AUTHORS WormBase. CONSRTM WormBase Consortium JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email: help@wormbase.org REFERENCE 2 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project: Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome Institute at Washington University, St. Louis, MO 63110, USA. REFERENCE 3 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. CONSRTM Caenorhabditis elegans Sequencing Consortium TITLE Genome sequence of the nematode C. elegans: a platform for investigating biology JOURNAL Science 282(5396), 2012-2018(1998). COMMENT Annotated features correspond to WormBase release WS292. Protein-coding gene structures below are the result of integration and manual review of the following types of data: ab initio predictions by Genefinder (P. Green and L. Hillier, pers. comm.); alignments to published proteins and cDNAs; genome sequence conservation with other nematodes (e.g. to C. briggsae using WABA: Genome Res. 2000. 10:1115-1125); sequence features (such as trans-splice and polyA sites). Sources of data: large-scale EST projects of Yuji Kohara (http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome cloning project (http://worfdb.dfci.harvard.edu); RST large-scale sequencing project (Genome Res. 2009. 19:2334-2342); IST library (Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010 Unpublished); UTRome EST data submission (UTRome v1 Mangone M. Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep sequencing data (454 read clusters - Makedonka Mitreva, unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66); Numerous data sets from the modENCODE project (Science. 2010. 330:1775-87); Individual C. elegans Nucleotide Database submissions; Personal communications with C. elegans researchers; Non-Coding gene structures below are derived using the following methods and data: ab initio prediction of tRNAs by tRNAscan-SE (Nucl. Acids. Res., 25, 955-964); integration and appraisal of miRNAs from miRBase (http://www.mirbase.org); integration and appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell. 2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87); manual curation of novel published ncRNAs from the literature. FEATURES Qualifiers source /organism="Caenorhabditis elegans" /chromosome="X" /strain="Bristol N2" /mol_type="genomic DNA" /db_xref="taxon:6239" protein /transl_table=1 /gene="mec-4" /locus_tag="CELE_T01C8.7" /standard_name="T01C8.7" /note="Confirmed by transcript evidence" /db_xref="WormBase:WBGene00003168" intron_pos 62:0 (1/14) intron_pos 147:1 (2/14) intron_pos 268:1 (3/14) intron_pos 305:2 (4/14) intron_pos 359:1 (5/14) intron_pos 409:0 (6/14) intron_pos 461:2 (7/14) intron_pos 491:1 (8/14) intron_pos 549:0 (9/14) intron_pos 581:0 (10/14) intron_pos 619:1 (11/14) intron_pos 639:2 (12/14) intron_pos 682:2 (13/14) intron_pos 708:0 (14/14) BEGIN 1 MSWMQNLKNY QHLRDPSEYM SQVYGDPLAY LQETTKFVTE REYYEDFGYG ECFNSTESEV 61 QCELITGEFD PKLLPYDKRL AWHFKEFCYK TSAHGIPMIG EAPNVYYRAV WVVLFLGCMI 121 MLYLNAQSVL DKYNRNEKIV DIQLKFDTAP FPAITLCNLN PYKASLATSV DLVKRTLSAF 181 DGAMGKAGGN KDHEEEREVV TEPPTTPAPT TKPARRRGKR DLSGAFFEPG FARCLCGSQG 241 SSEQEDKDEE KEEELLETTT KKVFNINDAD EEWDGMEEYD NEHYENYDVE ATTGMNMMEE 301 CQSERTKFDE PTGFDDRCIC AFDRSTHDAW PCFLNGTWET TECDTCNEHA FCTKDNKTAK 361 GHRSPCICAP SRFCVAYNGK TPPIEIWTYL QGGTPTEDPN FLEAMGFQGM TDEVAIVTKA 421 KENIMFAMAT LSMQDRERLS TTKRELVHKC SFNGKACDIE ADFLTHIDPA FGSCFTFNHN 481 RTVNLTSIRA GPMYGLRMLV YVNASDYMPT TEATGVRLTI HDKEDFPFPD TFGYSAPTGY 541 VSSFGLRLRK MSRLPAPYGD CVPDGKTSDY IYSNYEYSVE GCYRSCFQQL VLKECRCGDP 601 RFPVPENARH CDAADPIARK CLDARMNDLG GLHGSFRCRC QQPCRQSIYS VTYSPAKWPS 661 LSLQIQLGSC NGTAVECNKH YKENGAMVEV FYEQLNFEML TESEAYGFVN LLADFGGQLG 721 LWCGISFLTC CEFVFLFLET AYMSAEHNYS LYKKKKAEKA KKIASGSF //