LOCUS CCD65700.2 920 aa PRT CON 06-FEB-2024 DEFINITION Caenorhabditis elegans Caskin-2 protein. ACCESSION BX284606-265 PROTEIN_ID CCD65700.2 SOURCE Caenorhabditis elegans ORGANISM Caenorhabditis elegans Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. REFERENCE 1 (bases 1 to 17718942) AUTHORS WormBase. CONSRTM WormBase Consortium JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email: help@wormbase.org REFERENCE 2 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project: Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome Institute at Washington University, St. Louis, MO 63110, USA. REFERENCE 3 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. CONSRTM Caenorhabditis elegans Sequencing Consortium TITLE Genome sequence of the nematode C. elegans: a platform for investigating biology JOURNAL Science 282(5396), 2012-2018(1998). COMMENT Annotated features correspond to WormBase release WS292. Protein-coding gene structures below are the result of integration and manual review of the following types of data: ab initio predictions by Genefinder (P. Green and L. Hillier, pers. comm.); alignments to published proteins and cDNAs; genome sequence conservation with other nematodes (e.g. to C. briggsae using WABA: Genome Res. 2000. 10:1115-1125); sequence features (such as trans-splice and polyA sites). Sources of data: large-scale EST projects of Yuji Kohara (http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome cloning project (http://worfdb.dfci.harvard.edu); RST large-scale sequencing project (Genome Res. 2009. 19:2334-2342); IST library (Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010 Unpublished); UTRome EST data submission (UTRome v1 Mangone M. Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep sequencing data (454 read clusters - Makedonka Mitreva, unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66); Numerous data sets from the modENCODE project (Science. 2010. 330:1775-87); Individual C. elegans Nucleotide Database submissions; Personal communications with C. elegans researchers; Non-Coding gene structures below are derived using the following methods and data: ab initio prediction of tRNAs by tRNAscan-SE (Nucl. Acids. Res., 25, 955-964); integration and appraisal of miRNAs from miRBase (http://www.mirbase.org); integration and appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell. 2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87); manual curation of novel published ncRNAs from the literature. FEATURES Qualifiers source /organism="Caenorhabditis elegans" /chromosome="X" /strain="Bristol N2" /mol_type="genomic DNA" /db_xref="taxon:6239" protein /transl_table=1 /gene="C46H3.2" /locus_tag="CELE_C46H3.2" /standard_name="C46H3.2a" /note="Confirmed by transcript evidence" /db_xref="EnsemblGenomes-Gn:WBGene00016725" /db_xref="EnsemblGenomes-Tr:C46H3.2a" /db_xref="GOA:Q18662" /db_xref="InterPro:IPR001452" /db_xref="InterPro:IPR001660" /db_xref="InterPro:IPR002110" /db_xref="InterPro:IPR013761" /db_xref="InterPro:IPR020683" /db_xref="InterPro:IPR027013" /db_xref="InterPro:IPR035497" /db_xref="InterPro:IPR035498" /db_xref="InterPro:IPR036028" /db_xref="InterPro:IPR036770" /db_xref="UniProtKB/TrEMBL:Q18662" /db_xref="WormBase:WBGene00016725" intron_pos 16:1 (1/18) intron_pos 64:1 (2/18) intron_pos 113:0 (3/18) intron_pos 145:0 (4/18) intron_pos 182:0 (5/18) intron_pos 221:0 (6/18) intron_pos 259:1 (7/18) intron_pos 290:0 (8/18) intron_pos 341:1 (9/18) intron_pos 380:1 (10/18) intron_pos 406:2 (11/18) intron_pos 436:1 (12/18) intron_pos 476:0 (13/18) intron_pos 572:1 (14/18) intron_pos 673:0 (15/18) intron_pos 825:1 (16/18) intron_pos 864:2 (17/18) intron_pos 890:2 (18/18) BEGIN 1 MSSKKLLRRF SSSISDLLSI PKRDLCDNEE FTPLHNAVKM GNTVMAKNFI DSKSVWIDEP 61 DCRGQTALHL SITYGDTEMT SLLLKGGANV DSVDYDGISA CHIACKDGMI DHFNLLIYYH 121 ADICLVDRSG RTPFDLACEY GQEKMLERLF SCGLRKINFQ YMDHLHTASA FHLAAGSGQV 181 QILSMLLQHN WDLNFVTESG SALHMAAGSG QVQVVRFLLN SGIDINITNS DGLTAYAWAK 241 KNSSRNPITY KEIRFLLKNF HTFTNAVAVE DFCGVEANEL SLSIGDQVWV IERSTTQVWK 301 GIVFGRKGNS RSGFFQSNVI EDAGASDGIL TTPKIETRKN HNKMSSRLAK TPKNPTSTFS 361 KPVPAPAVPR RSCSIVQYHD INRNTPSQMS SFGRTTSCYG DTSNQRPNNM MTKSTSGSFG 421 SDSFHVFNGS RTSTPNPPTA MYSSSSCLYP VKVENHYASI GSSSSQSSSG FESAKCSTST 481 SASSFPSGVQ SNESGCESAH SVRSVESGSG SSSSIHGLDD SLYRSIHEVD VTSMVQSGVP 541 HAEVLANWLD SINMSNYLAV FLKQGYDLQT IARCTPADLL SLGIKNPDHR KKLMSDIHSW 601 KIIDQWPSVV PNNSLREWLH AIALAEYIPM FESQRYTSVS DVLDLQWEDF EDIGVKRLGH 661 LKRFGLTIKK LKDHQRHASN SLHPSHYAVH SNTSSYNSSY SSPQSFGYST PSPIQRQPAS 721 ASRLNDPPPP APSAPNRAFR ASCDKIDYLS YQQNNWKSAS ALPEAPAFLS VKPKSTSDLL 781 FGDDTPIRLN LVPTGKILSD ISKLKKDEEE DQELDDPNEC PPPPAPLHCN VGLHHISSGN 841 LSSFNSSLSN DQFPFANENC GTIRYSSTRP ATAFDIPAAL PPLLSDDHAS DHSSVGSCNK 901 PTIDEMLQDI QGAMDNLISS //